Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16296603 | 0.93 | TSHR (0.50) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL22394611 | 0.87 | TSHR (0.53) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1537333 | 0.87 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1004395 | 0.85 | TSHR (0.55) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| Hexane SCHEMBL5603076 | 0.83 | ALDH1A1 (0.54) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL311323 | 0.83 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL12677361 | 0.83 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL594507 | 0.83 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL311322 | 0.82 | TSHR (0.50) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| Oxirane SCHEMBL11032189 | 0.81 | TSHR (0.52) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216749-B2 | Curable composition, negative type color filter and method of producing the same | FUJIFILM CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20090092802-A1 | CURABLE COMPOSITION, NEGATIVE TYPE COLOR FILTER AND METHOD OF PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-7456237-B2 | Colorant-containing curable composition, color filter and method of producing the same | FUJIFILM CORPORATION (JP) | 2008-11-25 | — | — | US | disclosed |
| US-7169516-B2 | Dye-containing curable composition, color filter and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-30 | — | — | US | disclosed |
| US-6987174-B2 | Azo compound, colorant-containing curable composition, color filter and color filter production method | FUJI PHOTO FILM CO., LTD. (JP) | 2006-01-17 | — | — | US | disclosed |
| US-20050064307-A1 | Dye-containing negative-type curable composition, color filter, and method of producing the same | FUJI PHOTO FILM CO., LTD. | 2005-03-24 | — | — | US | disclosed |
| US-20050043452-A1 | Colorant-containing curable composition, color filter and method of producing the same | FUJI PHOTO FILM CO., LTD. | 2005-02-24 | — | — | US | disclosed |
| US-20050042530-A1 | Curable composition, negative type color filter and method of producing the same | FUJI PHOTO FILM CO., LTD. | 2005-02-24 | — | — | US | disclosed |
| EP-1508597-A1 | Curable composition, negative type color filter and method of producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-20040260075-A1 | Azo compound, colorant-containing curable composition, color filter and color filter production method | FUJI PHOTO FILM CO., LTD. | 2004-12-23 | — | — | US | disclosed |
| US-20040009414-A1 | Dye-containing curable composition, color filter and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2004-01-15 | — | — | US | disclosed |