Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.58 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.58 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.58 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.58 |
| ▸ | CBFB | Q13951 | 1/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | GNG2 | P59768 | 1/20 | 0.45 |
| ▸ | GNB1 | P62873 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163695 | 0.94 | KDM4E (0.65) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL4159315 | 0.87 | KDM4E (0.66) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL13696892 | 0.85 | KMT2A (0.55) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL29384128 | 0.85 | KDM4E (0.81) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL125080 | 0.85 | KDM4E (0.81) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL13697268 | 0.81 | KMT2A (0.61) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL4164355 | 0.81 | SMN1; SMN2 (0.53) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL4163110 | 0.78 | KMT2A (0.66) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL17154362 | 0.78 | KDM1A (0.74) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL17066272 | 0.77 | MDM4 (0.61) | KDM4EKMT2AMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9127164-B2 | Fluorescent dyes and uses thereof | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |
| EP-1940965-B1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ALMAC SCIENCES SCOTLAND LTD (GB) | 2014-03-26 | — | — | EP | disclosed |
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| EP-1940965-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI Scotland Limited (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049057-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ACR, ANXA5, GLB1 | KDM4E 4255/4885KMT2A 4502/4885MAPT 2114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.