Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.76 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 6/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4166472 | 0.91 | NR3C1 (0.64) | NR3C1ACLYCCR1SCN9ASCN10A | |
| SCHEMBL4168041 | 0.86 | NR3C1 (1.00) | NR3C1CYP3A4PGRCYP2C9 | |
| SCHEMBL4163647 | 0.86 | NR3C1 (0.68) | NR3C1ACLYCCR1SCN9ASCN10A | |
| SCHEMBL4158857 | 0.82 | NR3C1 (0.80) | NR3C1CCR1CYP3A4PGRCYP2C9 | |
| SCHEMBL14403954 | 0.82 | NR3C1 (0.82) | NR3C1CCR1CYP3A4PGRCYP2C9 | |
| SCHEMBL4164112 | 0.82 | NR3C1 (0.82) | NR3C1CCR1CYP3A4PGRCYP2C9 | |
| SCHEMBL4164098 | 0.82 | NR3C1 (0.91) | NR3C1CYP3A4PGRCYP2C9 | |
| SCHEMBL4170199 | 0.81 | NR3C1 (0.73) | NR3C1CCR1CYP3A4PGRCYP2C9 | |
| SCHEMBL4168046 | 0.81 | NR3C1 (0.72) | NR3C1ACLYCCR1SCN9ASCN10A | |
| SCHEMBL4158915 | 0.80 | NR3C1 (0.71) | NR3C1CCR1SCN9ACYP3A4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | BENGTSSON MALENA | 2009-07-02 | — | — | US | disclosed |
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | BENGTSSON MALENA | 2009-07-02 | — | — | US | disclosed |
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | BENGTSSON MALENA | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | NR3C1, NR3C2, NR5A1 | NR3C1 1/4885ACLY 2529/4885CCR1 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.