Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884908 | 0.75 | LIMK1 (0.39) | MAPTKDM4EALDH1A1HSD17B10LIMK1 | |
| SCHEMBL492415 | 0.75 | NPC1 (0.43) | MAPTKDM4ELIMK1CDC7CLK1 | |
| SCHEMBL2976564 | 0.75 | KAT2B (0.39) | MAPTKDM4EALDH1A1LIMK1CDC7 | |
| SCHEMBL4895675 | 0.75 | KAT2B (0.39) | MAPTKDM4EALDH1A1LIMK1CDC7 | |
| SCHEMBL24835668 | 0.71 | GRM4 (0.43) | MAPTKDM4EALDH1A1HSP90AA1KAT2B | |
| SCHEMBL493004 | 0.71 | L3MBTL1 (0.46) | MAPTKDM4EALDH1A1LIMK1CDC7 | |
| SCHEMBL18879061 | 0.71 | CYP2A6 (0.36) | MAPTKDM4EALDH1A1HSD17B10LIMK1 | |
| SCHEMBL492512 | 0.71 | KDM4E (0.34) | MAPTKDM4EALDH1A1LIMK1CDC7 | |
| SCHEMBL12603987 | 0.71 | GRM4 (0.40) | MAPTKDM4ELIMK1CDC7CLK1 | |
| SCHEMBL18238076 | 0.71 | NPC1 (0.35) | MAPTKDM4ELIMK1CDC7CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145009-A1 | HETEROCYCLIC COMPOUNDS THAT INHIBIT THE KINASE ACTIVITY OF MNK USEFUL FOR TREATING VARIOUS CANCERS | EFFECTOR THERAPEUTICS, INC. | 2017-05-25 | — | — | US | disclosed |
| EP-1915344-B1 | CYANOPYRIDINE PESTICIDES | BASF SE (DE) | 2009-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145009-A1 | HETEROCYCLIC COMPOUNDS THAT INHIBIT THE KINASE ACTIVITY OF MNK USEFUL FOR TREATING VARIOUS CANCERS | MAP3K9, MAP3K19, MAP3K20 | MAPT 2303/4885KDM4E 1316/4885ALDH1A1 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.