SCHEMBL4158701

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4167320	0.91	CDK2 (0.77)	CDK2CDK9CCNT1CCNA2CDK7
	SCHEMBL2076213	0.89	CDK2 (1.00)	CDK2CDK9CCNT1CCNA2CDK7
	SCHEMBL4158723	0.86	CDK9 (1.00)	CDK2CDK9CCNT1CCNA2CDK7
	SCHEMBL27664773	0.85	CDK2 (0.78)	CDK2CDK9CCNT1CCNA2CDK7
	SCHEMBL5159347	0.85	CDK2 (0.75)	CDK2CDK9CCNT1CCNA2CDK7
	SCHEMBL27664777	0.84	CDK2 (0.72)	CDK2CDK9CCNT1CCNA2CDK7
	SCHEMBL27664830	0.83	CDK2 (0.77)	CDK2CDK9CCNT1CCNA2CDK7
	SCHEMBL20451995	0.82	CDK4 (0.82)	CDK2CDK9CCNT1CCNA2CDK7
	SCHEMBL30777167	0.82	CDK4 (0.82)	CDK2CDK9CCNT1CCNA2CDK7
	SCHEMBL4156961	0.80	CDK2 (0.80)	CDK2CDK9CCNT1CCNA2CDK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.