Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4165476 | 0.81 | PRKAA2 (0.39) | SLC22A12NTRK1HCRTR1HCRTR2CNR1 | |
| SCHEMBL4170836 | 0.73 | HCRTR1 (0.38) | HCRTR1HCRTR2SPHK2SPHK1 | |
| SCHEMBL4166413 | 0.73 | HCRTR1 (0.38) | HCRTR1HCRTR2SPHK2SPHK1 | |
| SCHEMBL4161051 | 0.71 | RAB9A (0.40) | CNR1CNR2 | |
| SCHEMBL4158885 | 0.71 | HPGD (0.40) | PDE10A | |
| SCHEMBL4165466 | 0.71 | PDE4A (0.38) | SLC22A12HCRTR1HCRTR2SPHK2SPHK1 | |
| SCHEMBL1684252 | 0.66 | KMT2A (0.42) | HCRTR1HCRTR2CNR1CNR2 | |
| SCHEMBL16341513 | 0.66 | CHRM1 (0.63) | CNR1CNR2SPHK2CHRM1 | |
| SCHEMBL5864879 | 0.66 | HCRTR1 (0.44) | SLC22A12HCRTR1HCRTR2 | |
| SCHEMBL4918775 | 0.66 | HCRTR1 (0.44) | SLC22A12HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170846-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER INC | 2009-07-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170846-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | IMPDH1, IMPA1, TYMP | SLC22A12 2885/4885NTRK1 4719/4885FAP 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.