⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015069 | 0.78 | — | — | |
| SCHEMBL4210038 | 0.77 | ALOX5 (0.59) | — | |
| SCHEMBL11610370 | 0.77 | ALOX5 (0.43) | — | |
| SCHEMBL4210041 | 0.77 | ALOX5 (0.59) | — | |
| SCHEMBL1616182 | 0.74 | — | — | |
| SCHEMBL1616183 | 0.74 | — | — | |
| Formic Acid SCHEMBL27610067 | 0.74 | ALOX5 (0.39) | — | |
| SCHEMBL3094620 | 0.72 | — | — | |
| SCHEMBL487376 | 0.72 | — | — | |
| SCHEMBL8815406 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-04-23 | — | — | US | claimed |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | US | claimed |
| CN-1950375-A | Glucocorticoid receptor modulator compounds and methods- utility | LIGAND PHARM INC (US) | 2007-04-18 | — | — | CN | claimed |
| EP-1718653-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | Ligand Pharmaceuticals Inc. (US) | 2006-11-08 | — | — | EP | claimed |
| CN-1264819-C | Stereoselective synthesis method of prostacyclin derivative | UNITED THERAPEUTICS CORP (US) | 2006-07-19 | — | — | CN | claimed |
| WO-2005082909-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2005-09-09 | — | — | WO | claimed |
| CN-1283184-A | Stereoselective synthesis method of prostacyclin derivative | UNITED THERAPEUTICS CORP (US) | 2001-02-07 | — | — | CN | claimed |
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-04-23 | — | — | US | disclosed |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | US | disclosed |
| CN-1950375-A | Glucocorticoid receptor modulator compounds and methods- utility | LIGAND PHARM INC (US) | 2007-04-18 | — | — | CN | disclosed |
| EP-1718653-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | Ligand Pharmaceuticals Inc. (US) | 2006-11-08 | — | — | EP | disclosed |
| CN-1264819-C | Stereoselective synthesis method of prostacyclin derivative | UNITED THERAPEUTICS CORP (US) | 2006-07-19 | — | — | CN | disclosed |
| WO-2005082909-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2005-09-09 | — | — | WO | disclosed |
| CN-1283184-A | Stereoselective synthesis method of prostacyclin derivative | UNITED THERAPEUTICS CORP (US) | 2001-02-07 | — | — | CN | disclosed |