SCHEMBL4159098

SCHEMBL4159098

CC=NOCC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10902595 1.00
SCHEMBL18102293 0.76
SCHEMBL16046967 0.75 GPR55 (0.39)
SCHEMBL16046968 0.75 GPR55 (0.39)
SCHEMBL21549647 0.75
SCHEMBL19295802 0.75 MAPK1 (0.34)
SCHEMBL12268278 0.75
SCHEMBL22688559 0.75 GPR55 (0.39)
SCHEMBL14601171 0.75 GPR55 (0.39)
SCHEMBL9803634 0.73 GAA (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090105292-A9 Glucocorticoid Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2009-04-23 US claimed
US-20070281959-A1 Glucocorticoid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2007-12-06 US claimed
EP-1718653-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY Ligand Pharmaceuticals Inc. (US) 2006-11-08 EP claimed
WO-2005082909-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY LIGAND PHARMACEUTICALS INCORPORATED (US) 2005-09-09 WO claimed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-10800816-B2 TFPI inhibitors and methods of use Baxalta GmbH (CH) 2020-10-13 US disclosed
EP-2827883-B1 TFPI INHIBITORS AND METHODS OF USE Baxalta GmbH (CH) 2019-05-08 EP disclosed
US-20180155399-A1 TFPI INHIBITORS AND METHODS OF USE Baxalta GmbH (CH) 2018-06-07 US disclosed
US-9873720-B2 TFPI inhibitors and methods of use Baxalta GmbH (CH) 2018-01-23 US disclosed
US-20170174727-A1 TFPI INHIBITORS AND METHODS OF USE Baxalta GmbH (CH) 2017-06-22 US disclosed
US-8962563-B2 TFPI inhibitors and methods of use BAXTER INTERNATIONAL, INC. (US) 2015-02-24 US disclosed
EP-2827883-A1 TFPI INHIBITORS AND METHODS OF USE Baxter International Inc (US) 2015-01-28 EP disclosed
US-20130252896-A1 TFPI INHIBITORS AND METHODS OF USE BAXTER HEALTHCARE SA (CH) 2013-09-26 US disclosed
US-20090105292-A9 Glucocorticoid Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2009-04-23 US disclosed
US-20070281959-A1 Glucocorticoid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2007-12-06 US disclosed
EP-1718653-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY Ligand Pharmaceuticals Inc. (US) 2006-11-08 EP disclosed
WO-2005082909-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY LIGAND PHARMACEUTICALS INCORPORATED (US) 2005-09-09 WO disclosed
US-5840758-A USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES ABBOTT LABORATORIES (US) 1998-11-24 US disclosed
US-4584014-A PREEMERGENCE HERBICIDES;CORN, WHEAT AND OATS ROHM AND HAAS COMPANY (US) 1986-04-22 US disclosed
US-4584014-A PREEMERGENCE HERBICIDES;CORN, WHEAT AND OATS ROHM AND HAAS COMPANY (US) 1986-04-22 US disclosed