Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RORC | P51449 | 5/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4174122 | 0.91 | ALDH1A1 (0.39) | ALDH1A1RORCTMIGD3ADORA1HSD17B10 | |
| SCHEMBL4167211 | 0.89 | CTPS1 (0.39) | ALDH1A1RORCTMIGD3ADORA1HSD17B10 | |
| SCHEMBL1621732 | 0.85 | ALDH1A1 (0.61) | ALDH1A1RORCADORA1HSD17B10HPGD | |
| SCHEMBL1621586 | 0.85 | ADORA1 (0.58) | RORCTMIGD3ADORA1HSD17B10LMNA | |
| SCHEMBL1621410 | 0.76 | MAPT (0.54) | ALDH1A1RORCMAPTLMNAUSP2 | |
| SCHEMBL1621250 | 0.75 | ALDH1A1 (0.58) | ALDH1A1RORCHSD17B10HPGDMAPT | |
| SCHEMBL1622016 | 0.75 | ALDH1A1 (0.55) | ALDH1A1RORCADORA1HSD17B10HPGD | |
| SCHEMBL1466192 | 0.73 | ALDH1A1 (0.60) | ALDH1A1RORCADORA1HSD17B10HPGD | |
| SCHEMBL3659566 | 0.73 | ALDH1A1 (0.54) | ALDH1A1RORCHSD17B10HPGDTSHR | |
| SCHEMBL4073631 | 0.73 | MEN1 (0.40) | ALDH1A1RORCTMIGD3ADORA1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |