Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 15/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151827 | 0.93 | PTGER1 (0.57) | PTGER1CYP2C9MRGPRX4LRRK2 | |
| SCHEMBL13697145 | 0.90 | PTGER1 (0.73) | PTGER1CYP2C9RXRARXRBRXRG | |
| SCHEMBL4155029 | 0.90 | PTGER1 (0.51) | PTGER1CYP2C9MRGPRX4 | |
| SCHEMBL4159371 | 0.88 | PTGER1 (0.68) | PTGER1CYP2C9RXRARXRBRXRG | |
| SCHEMBL5620357 | 0.87 | PTGER1 (0.64) | PTGER1CYP2C9MRGPRX4RXRARXRB | |
| SCHEMBL13697443 | 0.87 | PTGER1 (0.48) | PTGER1CYP2C9MRGPRX4 | |
| SCHEMBL5621090 | 0.87 | PTGER1 (0.63) | PTGER1CYP2C9MRGPRX4RXRARXRB | |
| SCHEMBL5620237 | 0.87 | PTGER1 (0.82) | PTGER1CYP2C9 | |
| SCHEMBL4168385 | 0.86 | PTGER1 (0.47) | PTGER1CYP2C9MRGPRX4 | |
| SCHEMBL5620146 | 0.86 | PTGER1 (0.62) | PTGER1CYP2C9MRGPRX4RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | PTGER1 246/4885CYP2C9 5/4885MRGPRX4 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.