SCHEMBL4159767

SCHEMBL4159767

BrCC(Br)COc1c(Br)cc(CCCc2cc(Br)c(OCC(Br)CBr)c(Br)c2)cc1Br

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
THRB P10828 16/20 0.42
THRA P10827 15/20 0.42
HRH3 Q9Y5N1 3/20 0.41
ESR1 P03372 1/20 0.32
NR3C1 P04150 1/20 0.32
PGR P06401 1/20 0.32
NR3C2 P08235 1/20 0.32
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16164120 0.93 ALDH1A1 (0.63) ALDH1A1THRBTHRAHRH3ESR1
SCHEMBL16164205 0.89 ALDH1A1 (0.49) ALDH1A1THRBTHRAHRH3
SCHEMBL4082525 0.87 ALDH1A1 (0.60) ALDH1A1THRBTHRAHRH3
SCHEMBL5432306 0.86 ALDH1A1 (0.63) ALDH1A1THRBTHRAHRH3
SCHEMBL28796079 0.85 ALDH1A1 (0.52) ALDH1A1THRBTHRAHRH3
SCHEMBL16164068 0.85 ALDH1A1 (0.46) ALDH1A1THRBTHRA
SCHEMBL28421240 0.83 ALDH1A1 (0.64) ALDH1A1THRBTHRAHRH3
SCHEMBL5440832 0.82 ALDH1A1 (0.67) ALDH1A1THRBTHRA
SCHEMBL5428071 0.82 ALDH1A1 (0.67) ALDH1A1THRBTHRA
SCHEMBL16164498 0.82 ALDH1A1 (0.51) ALDH1A1THRBTHRAHRH3ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137174-A1 FLAME-RETARDANT POLYMERIC COMPOSITIONS POLYMER PRODUCTS COMPANY, INC. (US) 2009-05-28 US claimed
JP-4234337-A None JP disclosed
JP-4270236-A None JP disclosed
EP-3202842-B1 FIBER-REINFORCED POLYPROPYLENE FLAME-RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE USING SAME JAPAN POLYPROPYLENE CORP (JP) 2021-08-11 EP disclosed
US-10233317-B2 Fiber-reinforced flame-retardant polypropylene resin composition and molded article using the same JAPAN POLYPROPYLENE CORPORATION (JP) 2019-03-19 US disclosed
EP-3202842-A1 FIBER-REINFORCED POLYPROPYLENE FLAME-RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE USING SAME Japan Polypropylene Corporation (JP) 2017-08-09 EP disclosed
US-20170218189-A1 FIBER-REINFORCED FLAME-RETARDANT POLYPROPYLENE RESIN COMPOSITION AND MOLDED ARTICLE USING THE SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2017-08-03 US disclosed
US-9321897-B2 Thermoplastic resin composition and toilet components made therefrom JAPAN POLYPROPYLENE CORPORATION (JP) 2016-04-26 US disclosed
US-20140309350-A1 THERMOPLASTIC RESIN COMPOSITION AND TOILET COMPONENTS MADE THEREFROM JAPAN POLYPROPYLENE CORPORATION (JP) 2014-10-16 US disclosed
US-20090137174-A1 FLAME-RETARDANT POLYMERIC COMPOSITIONS POLYMER PRODUCTS COMPANY, INC. (US) 2009-05-28 US disclosed
JP-H04270236-A SEPARATION AND RECOVERY OF BIS(3,5-DIBROMO-4-DIBROMOPROPOXYPHENYL)PROPANE TOSOH CORP 1992-09-25 JP disclosed
JP-H04234337-A SEPARATION AND RECOVERY OF BIS(3,5-DIBROMO-4-DIBROMOPROPOXYPHENYL)PROPANE TOSOH CORP 1992-08-24 JP disclosed