Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.45 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.37 |
| ▸ | PRKCG | P05129 | 2/20 | 0.37 |
| ▸ | PRKCB | P05771 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050737 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL8813994 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL8811352 | 1.00 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL4499982 | 0.95 | CES2 (0.46) | CES2THRBGMNNTP53POLB | |
| SCHEMBL7001843 | 0.95 | CES2 (0.46) | CES2THRBGMNNTP53POLB | |
| SCHEMBL7000978 | 0.95 | CES2 (0.46) | CES2THRBGMNNTP53POLB | |
| SCHEMBL10590914 | 0.95 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL14814300 | 0.95 | CES2 (0.52) | CES2THRBGMNNTP53POLB | |
| SCHEMBL14814096 | 0.92 | CES2 (0.48) | CES2THRBGMNNTP53POLB | |
| SCHEMBL6721928 | 0.92 | CES2 (0.43) | CES2THRBGMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402183-A | Boron-containing compound and medical application thereof | 正大天晴药业集团股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| US-10954351-B2 | Aprotic polymer-molten salt-solvent ternary composition, method for the preparation and use thereof in electrochemical systems | HYDRO-QUéBEC (CA) | 2021-03-23 | — | — | US | disclosed |
| US-20180155513-A1 | APROTIC POLYMER/MOLTEN SALT TERNARY MIXTURE SOLVENT, METHOD FOR THE PRODUCTION AND USE THEREOF IN ELECTROCHEMICAL SYSTEMS | HYDRO-QUéBEC (CA) | 2018-06-07 | — | — | US | disclosed |
| WO-2014121036-A1 | 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | DEUTERX, LLC (US) | 2014-08-07 | — | — | WO | disclosed |
| US-20140221369-A1 | 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | DEUTERX, LLC (US) | 2014-08-07 | — | — | US | disclosed |
| US-20090263723-A9 | APROTIC POLYMER/MOLTEN SALT TERNARY MIXTURE SOLVENT, METHOD FOR THE PRODUCTION AND USE THEREOF IN ELECTROCHEMICAL SYSTEMS | HYDRO-QUEBEC (CA) | 2009-10-22 | — | — | US | disclosed |
| EP-2074089-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2009-07-01 | — | — | EP | disclosed |
| US-20090029263-A1 | APROTIC POLYMER/MOLTEN SALT TERNARY MIXTURE SOLVENT, METHOD FOR THE PRODUCTION AND USE THEREOF IN ELECTROCHEMICAL SYSTEMS | HYDRO-QUEBEC (CA) | 2009-01-29 | — | — | US | disclosed |
| WO-2008048991-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-04-24 | — | — | WO | disclosed |
| EP-0718688-B1 | Photographic element containing a novel cyan dye forming coupler and process for its use | EASTMAN KODAK CO (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-0718688-A1 | Photographic element containing a novel cyan dye forming coupler and process for its use | EASTMAN KODAK COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| US-4587050-A | Substituted enantholactam derivatives as antihypertensives | MERCK & CO., INC. (US) | 1986-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221369-A1 | 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | SRD5A2, PPARD, SRD5A1 | CES2 3791/4885THRB 545/4885GMNN 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.