Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 15/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158285 | 0.95 | PTGER1 (0.54) | PTGER1CYP2C9MAOBMRGPRX4MAPT | |
| SCHEMBL4446141 | 0.93 | PTGER1 (0.51) | PTGER1CYP2C9MAOBMRGPRX4 | |
| SCHEMBL4149741 | 0.92 | PTGER1 (0.61) | PTGER1CYP2C9MAOBMRGPRX4RXRA | |
| SCHEMBL4154952 | 0.89 | PTGER1 (0.48) | PTGER1CYP2C9MAOBMRGPRX4RXRA | |
| SCHEMBL13697469 | 0.89 | PTGER1 (0.61) | PTGER1CYP2C9MRGPRX4RXRARXRB | |
| SCHEMBL4154080 | 0.88 | PTGER1 (0.54) | PTGER1CYP2C9RXRARXRBRXRG | |
| SCHEMBL13697510 | 0.88 | PTGER1 (0.51) | PTGER1CYP2C9MAOBMRGPRX4MAPT | |
| SCHEMBL13697509 | 0.85 | PTGER1 (0.49) | PTGER1CYP2C9MAOBMRGPRX4 | |
| SCHEMBL4149637 | 0.85 | PTGER1 (0.55) | PTGER1CYP2C9 | |
| SCHEMBL4160136 | 0.85 | PTGER1 (0.45) | PTGER1CYP2C9MAOBMRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | PTGER1 246/4885CYP2C9 5/4885MAOB 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.