Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20921259 | 1.00 | KMT2A (0.44) | KMT2APTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL6017451 | 0.81 | KMT2A (0.47) | KMT2APTGS1PTGS2ALDH1A1MT-CO2 | |
| SCHEMBL6240135 | 0.81 | KMT2A (0.47) | KMT2APTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL27706318 | 0.80 | KMT2A (0.47) | KMT2AALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL3928247 | 0.80 | KMT2A (0.43) | KMT2APTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL3921752 | 0.80 | KMT2A (0.43) | KMT2AALDH1A1KDM1A | |
| SCHEMBL1345444 | 0.79 | GABRA1 (0.52) | KMT2APTGS1PTGS2ALDH1A1MT-CO2 | |
| SCHEMBL31517035 | 0.79 | GABRA1 (0.52) | KMT2APTGS1PTGS2ALDH1A1MT-CO2 | |
| SCHEMBL5541713 | 0.79 | LPAR1 (0.49) | KMT2APTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL15539819 | 0.79 | KMT2A (0.42) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114292226-B | Compound with hydroxamic acid structure and preparation method and application thereof | 沈阳药科大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-113372184-A | Method for synthesizing C-N axis chiral phenanthridinone compound based on chiral transfer strategy | 武汉大学 | 2021-09-10 | — | — | CN | disclosed |
| CN-109776295-A | A kind of aryl iodine compound and preparation method of the ortho position containing difluoro methylene | 浙江师范大学 | 2019-05-21 | — | — | CN | disclosed |
| US-8264140-B2 | Organic electroluminescence element and display device | FUJI XEROX CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-20090039774-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND DISPLAY DEVICE | FUJI XEROX CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| CN-1046711-C | Unsaturated hydroxyalkyl quinoline carboxylic acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1999-11-24 | — | — | CN | disclosed |
| US-5856322-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1999-01-05 | — | — | US | disclosed |
| EP-0480717-B1 | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1998-04-15 | — | — | EP | disclosed |
| US-5565473-A | USEFUL AS ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND CYTOPROTECTIVE AGENTS; MONTELUKAST AND ITS SODIUM SALT | MERCK FROSST CANADA, INC. (CA) | 1996-10-15 | — | — | US | disclosed |
| US-5270324-A | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1993-12-14 | — | — | US | disclosed |
| CN-1061407-A | Unsaturated hydroxyalkyl quinoline carboxylic acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1992-05-27 | — | — | CN | disclosed |
| EP-0480717-A1 | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |