Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 16/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 16/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 13/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.50 |
| ▸ | USP2 | O75604 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103599 | 0.84 | MAPT (0.62) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4011562 | 0.75 | PI4KB (0.62) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4359058 | 0.75 | CYP1A2 (0.56) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4013688 | 0.74 | MAPK1 (0.67) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4014696 | 0.74 | MAPT (0.63) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL14026142 | 0.72 | MAPK1 (0.72) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4007243 | 0.72 | CYP1A2 (0.67) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4007548 | 0.70 | MAPK1 (0.63) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4892645 | 0.70 | PRKDC (0.45) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4008515 | 0.70 | MAPT (0.80) | CYP1A2CYP3A4CLK4CYP2D6USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844004-B1 | QUINAZOLINE DERIVATES AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LTD (GB) | 2009-06-24 | — | — | EP | disclosed |