Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 8/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167830 | 0.89 | AR (0.40) | NR1H2NR1H3ARSLC22A12PGR | |
| SCHEMBL27786939 | 0.85 | NR1H2 (0.46) | NR1H2NR1H3MEN1KMT2APOLB | |
| SCHEMBL4167355 | 0.85 | NR1H2 (0.44) | NR1H2NR1H3MEN1KMT2APOLB | |
| SCHEMBL4160610 | 0.82 | NR1H2 (0.40) | NR1H2NR1H3ARKMT2APGR | |
| SCHEMBL4174648 | 0.81 | NR1H2 (0.46) | NR1H2NR1H3MEN1KMT2APOLB | |
| SCHEMBL4156280 | 0.80 | NR1H2 (0.45) | NR1H2NR1H3MEN1KMT2APOLB | |
| SCHEMBL4174108 | 0.78 | NR1H3 (0.46) | NR1H2NR1H3MEN1KMT2APOLB | |
| SCHEMBL4167820 | 0.76 | AR (0.38) | NR1H2NR1H3ARPGRSCN9A | |
| SCHEMBL4165449 | 0.75 | NR1H2 (0.44) | NR1H2NR1H3PIK3CDSCN9A | |
| SCHEMBL27796471 | 0.75 | NR1H2 (0.48) | NR1H2NR1H3MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |