Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33773 | 0.88 | TDP1 (0.44) | ALOX15HSD17B10LDHALDHBGRIK1 | |
| SCHEMBL1809603 | 0.85 | ALOX15 (0.57) | ALOX15HSD17B10LDHAGRIK1GRIK2 | |
| Itaconate SCHEMBL28511688 | 0.83 | ALOX15 (0.65) | ALOX15HSD17B10LDHALDHBGRIK1 | |
| SCHEMBL10380940 | 0.80 | — | — | |
| SCHEMBL514158 | 0.80 | — | — | |
| SCHEMBL370643 | 0.80 | — | — | |
| Itaconate SCHEMBL27560826 | 0.79 | ALOX15 (0.60) | ALOX15HSD17B10LDHALDHBGRIK1 | |
| Itaconate SCHEMBL28310540 | 0.79 | ALOX15 (0.54) | ALOX15HSD17B10LDHALDHBGRIK1 | |
| Carbimide SCHEMBL7758388 | 0.78 | TDP1 (0.36) | TDP1ALDH1A1LMNAOR51E2 | |
| SCHEMBL6901765 | 0.78 | TDP1 (0.36) | TDP1ALDH1A1LMNAOR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090212035-A1 | Glow plug and methods for the production thereof | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDETEN FORSCHUNG E.V. (DE) | 2009-08-27 | — | — | US | disclosed |