Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.61 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.61 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.61 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | FGR | P09769 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037057 | 0.92 | ADORA2A (0.73) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA | |
| SCHEMBL6273633 | 0.88 | ADORA2A (0.79) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA | |
| SCHEMBL11536543 | 0.87 | P2RY4 (0.60) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA | |
| SCHEMBL11536541 | 0.87 | P2RY4 (0.63) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA | |
| SCHEMBL28200966 | 0.84 | MEN1 (0.62) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA | |
| SCHEMBL10809232 | 0.83 | P2RY4 (0.60) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA | |
| SCHEMBL14566056 | 0.83 | ADORA2A (0.70) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA | |
| SCHEMBL18157069 | 0.82 | THRB (0.47) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA | |
| SCHEMBL169365 | 0.82 | ADORA2A (0.63) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA | |
| SCHEMBL30918998 | 0.82 | ADORA2A (0.63) | ADORA2ACSNK1A1CSNK1DCSNK1G1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443101-B1 | BAIT CHEMISTRIES IN HYDROGEL PARTICLES FOR SERUM BIOMARKER ANALYSIS | LIOTTA LANCE (US) | 2019-03-27 | — | — | EP | disclosed |
| US-20120107959-A1 | BAIT CHEMISTRIES IN HYDROGEL PARTICLES FOR SERUM BIOMARKER ANALYSIS | NNSA | 2012-05-03 | — | — | US | disclosed |