Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 11/20 | 0.41 |
| ▸ | FAP | Q12884 | 6/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160587 | 0.92 | CTSL (0.40) | CTSLCTSSCTSKSCN9ATACR1 | |
| SCHEMBL4168944 | 0.85 | DPP4 (0.57) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL4168946 | 0.85 | DPP4 (0.57) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL4102277 | 0.84 | SCN9A (0.55) | CTSLCTSSCTSKSCN9ATACR1 | |
| SCHEMBL4119690 | 0.84 | SCN9A (0.55) | CTSLCTSSCTSKSCN9ATACR1 | |
| SCHEMBL4174694 | 0.84 | CTSL (0.41) | CTSLCTSSCTSKSCN9ATACR1 | |
| SCHEMBL4164936 | 0.83 | CTSL (0.47) | CTSLCTSSCTSKSCN9ADPP4 | |
| SCHEMBL4113611 | 0.83 | MEN1 (0.37) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL4158311 | 0.74 | SCN9A (0.46) | CTSLCTSSCTSKSCN9ADPP4 | |
| SCHEMBL4166330 | 0.74 | CTSL (0.46) | CTSLCTSSCTSKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149504-A1 | Novel 5-Substituted Indole Derivatives As Dipeptidyl Peptidase IV (DPP-IV) Inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149504-A1 | Novel 5-Substituted Indole Derivatives As Dipeptidyl Peptidase IV (DPP-IV) Inhibitors | DPP4, DPP3, DPP7 | CTSL 394/4885CTSS 1084/4885CTSK 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.