Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18979954 | 0.83 | MAPT (0.41) | DRD2DRD3OPRM1 | |
| SCHEMBL14515649 | 0.81 | SMPD3 (0.50) | MTNR1AMTNR1BOPRM1OPRK1OGFRL1 | |
| SCHEMBL17844913 | 0.81 | KMT2A (0.47) | DRD2DRD3OPRK1 | |
| SCHEMBL20293037 | 0.78 | DYRK1A (0.59) | — | |
| Hydrochloric Acid SCHEMBL30114327 | 0.77 | PBK (0.47) | OPRM1OPRK1 | |
| SCHEMBL3937807 | 0.77 | MALT1 (0.58) | OPRK1 | |
| SCHEMBL3937794 | 0.77 | MALT1 (0.58) | OPRK1 | |
| SCHEMBL23830989 | 0.76 | KDM4E (0.55) | — | |
| SCHEMBL18228083 | 0.76 | KDM4E (0.55) | — | |
| SCHEMBL17506213 | 0.76 | MEN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | BENGTSSON MALENA | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | NR3C1, NR3C2, NR5A1 | MTNR1A 214/4885MTNR1B 191/4885DRD2 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.