⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669647 | 0.70 | — | — | |
| SCHEMBL15598917 | 0.70 | — | — | |
| SCHEMBL22862335 | 0.69 | TAAR1 (0.76) | — | |
| SCHEMBL22130289 | 0.67 | — | — | |
| SCHEMBL5154431 | 0.66 | — | — | |
| SCHEMBL13798845 | 0.66 | — | — | |
| SCHEMBL31420810 | 0.64 | — | — | |
| SCHEMBL573723 | 0.63 | — | — | |
| SCHEMBL2140847 | 0.63 | FABP1 (0.47) | — | |
| SCHEMBL13647285 | 0.63 | TAAR1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668182-B1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC DISCOVERY GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| EP-2668183-B1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC DISCOVERY GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-8940888-B2 | Hydrazido derivatives of hyaluronic acid | PROCHON BIOTECH LTD. (US) | 2015-01-27 | — | — | US | disclosed |
| US-20140005141-A1 | HYDRAZIDO DERIVATIVES OF HYALURONIC ACID | BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) | 2014-01-02 | — | — | US | disclosed |
| EP-2668182-A1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC Discovery GmbH (DE) | 2013-12-04 | — | — | EP | disclosed |
| EP-2668183-A1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC Discovery GmbH (DE) | 2013-12-04 | — | — | EP | disclosed |
| US-8592456-B2 | IL17 and IFN-gamma inhibition for the treatment of autoimmune inflammation | 4SC DISCOVERY GMBH (DE) | 2013-11-26 | — | — | US | disclosed |
| US-8524885-B2 | Hydrazido derivatives of hyaluronic acid | PROCHON BIOTECH LTD. (IL) | 2013-09-03 | — | — | US | disclosed |
| US-8354436-B2 | IL17 and IFN-gamma inhibition for the treatment of autoimmune inflammation | 4SC DISCOVERY GMBH (DE) | 2013-01-15 | — | — | US | disclosed |
| EP-2492285-A1 | Hydrazido derivatives of hyaluronic acid | ProChon Biotech Ltd. (IL) | 2012-08-29 | — | — | EP | disclosed |
| US-20120196861-A1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC DISCOVERY GMBH (DE) | 2012-08-02 | — | — | US | disclosed |
| US-20120196862-A1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC DISCOVERY GMBH (DE) | 2012-08-02 | — | — | US | disclosed |
| WO-2012101261-A1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC DISCOVERY GMH (DE) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012101263-A1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC DISCOVERY GMBH (DE) | 2012-08-02 | — | — | WO | disclosed |
| US-20090149419-A1 | HYDRAZIDO DERIVATIVES OF HYALURONIC ACID | PROCHON BIOTECH LTD. (IL) | 2009-06-11 | — | — | US | disclosed |
| US-4330544-A | Amino-alkoxy pyrazoles and pharmaceutical compositions | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1982-05-18 | — | — | US | disclosed |