⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14125002 | 0.67 | NOTUM (0.56) | — | |
| SCHEMBL11149894 | 0.65 | — | — | |
| SCHEMBL12427497 | 0.65 | — | — | |
| SCHEMBL1351742 | 0.64 | NOTUM (0.63) | — | |
| SCHEMBL4163797 | 0.63 | — | — | |
| SCHEMBL11735548 | 0.62 | — | — | |
| SCHEMBL7238701 | 0.62 | — | — | |
| SCHEMBL2009212 | 0.62 | — | — | |
| SCHEMBL7239683 | 0.62 | — | — | |
| SCHEMBL11149882 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4071147-B1 | NOVEL AMINO ARYL DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR AND USE THEREOF | LG CHEMICAL LTD (KR) | 2025-03-26 | — | — | EP | claimed |
| CN-115594691-B | Synthetic method of isoxazolo [4,5-b ] pyridine-6-ketone compound | 五邑大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117700407-A | 3, 3-disubstituted indol-2-one compound and preparation method and application thereof | 五邑大学 | 2024-03-15 | — | — | CN | claimed |
| CN-117630218-A | High performance liquid chromatography detection method for sodium sulfaisoxazole intermediate and isomer thereof | 江苏天和制药有限公司 | 2024-03-01 | — | — | CN | claimed |
| EP-3801529-B1 | HIGHLY POTENT TACC3 INHIBITOR AS A NOVEL ANTICANCER DRUG CANDIDATE | ONCOCUBE THERAPEUTICS LLC (US) | 2023-10-11 | — | — | EP | claimed |
| CN-115594691-A | Synthesis method of isoxazolo [4,5-b ] pyridine-6-ketone compound | 五邑大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115279754-A | Isoxazole derivatives targeting TACC3 as anticancer agents | A2A制药有限公司 | 2022-11-01 | — | — | CN | claimed |
| EP-4058447-A1 | ISOXAZOLE DERIVATIVES TARGETING TACC3 AS ANTICANCER AGENTS | A2A Pharmaceuticals, Inc. (US) | 2022-09-21 | — | — | EP | claimed |
| CN-113416171-A | 4, 5-dihydronaphthoisoxazole derivatives and application thereof in antitumor drugs | 守恒(厦门)医疗科技有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-113321645-A | 5-aminoisoxazole derivative and application thereof in preparation of multi-kinase inhibitor | 苏州安睿药业有限公司 | 2021-08-31 | — | — | CN | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| US-5830867-A | Hemoregulatory peptides for stimulating the myelopoietic system | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-03 | — | — | US | claimed |
| EP-0701446-A4 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1997-04-23 | — | — | EP | claimed |
| EP-0701446-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-20 | — | — | EP | claimed |
| WO-1994027627-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | claimed |
| EP-0248399-A1 | Aminoazole derivatives and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-12-09 | — | — | EP | claimed |
| EP-0090275-B1 | ISOXAZOLE (5,4-B) PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-10-28 | — | — | EP | claimed |
| EP-0043024-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO ISOXAZOLES | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1984-03-28 | — | — | EP | claimed |
| EP-0043024-A1 | Process for the preparation of 5-amino isoxazoles | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1982-01-06 | — | — | EP | claimed |
| EP-0002881-A1 | 5-Isoxazolylurea derivatives, their preparation, their use and compositions containing them | FISONS plc (GB) | 1979-07-11 | — | — | EP | claimed |