Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.73 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.73 |
| ▸ | MMP9 | P14780 | 10/20 | 0.61 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3013315 | 0.88 | MMP2 (0.92) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL3009401 | 0.88 | MMP2 (0.92) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL3009406 | 0.88 | MMP2 (0.92) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL3890915 | 0.86 | MMP2 (0.76) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL3890918 | 0.86 | MMP2 (0.76) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL3887007 | 0.86 | MMP2 (0.68) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL5121167 | 0.85 | MMP2 (0.74) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL5117214 | 0.85 | MMP2 (0.74) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL13890444 | 0.85 | MMP2 (0.74) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL4173843 | 0.85 | MMP2 (0.63) | MMP2ADAMTS5MMP9ADAMTS4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111860-A1 | SULFONAMIDE COMPOUNDS USEFUL AS ADG RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111860-A1 | SULFONAMIDE COMPOUNDS USEFUL AS ADG RECEPTOR MODULATORS | ADGRE5, ADGRF1, SELPLG | MMP2 3625/4885ADAMTS5 891/4885MMP9 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.