Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11669735 | 0.85 | TSHR (0.56) | RAB9AMEN1KMT2AMAOBTSHR | |
| SCHEMBL2911594 | 0.79 | MAOB (0.80) | MEN1KMT2AMAOBALDH1A1CA12 | |
| SCHEMBL28690961 | 0.79 | TSHR (0.59) | MEN1KMT2AMAOBTSHRALDH1A1 | |
| SCHEMBL10900936 | 0.78 | TSHR (0.66) | RAB9AMEN1KMT2AMAOBTSHR | |
| SCHEMBL4440051 | 0.78 | ALDH1A1 (0.57) | RAB9AMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL11669017 | 0.78 | TSHR (0.51) | RAB9AMEN1KMT2AMAOBTSHR | |
| SCHEMBL4173474 | 0.78 | SLC16A3 (0.51) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL8927648 | 0.78 | TSHR (0.70) | RAB9AMEN1KMT2AMAOBTSHR | |
| SCHEMBL29389855 | 0.78 | TSHR (0.70) | RAB9AMEN1KMT2AMAOBTSHR | |
| SCHEMBL21273274 | 0.76 | SIRT2 (0.44) | RAB9AMAOBALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082577-A1 | FLUORESCENT PROBES FOR BIOLOGICAL STUDIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-03-26 | — | — | US | disclosed |
| US-20090082577-A1 | FLUORESCENT PROBES FOR BIOLOGICAL STUDIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-03-26 | — | — | US | disclosed |
| US-20090082577-A1 | FLUORESCENT PROBES FOR BIOLOGICAL STUDIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-03-26 | — | — | US | disclosed |
| US-7442529-B2 | Fluorescent probes for biological studies | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442529-B2 | Fluorescent probes for biological studies | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-28 | — | — | US | disclosed |
| US-20060234206-A1 | Fluorescent probes for biological studies | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082577-A1 | FLUORESCENT PROBES FOR BIOLOGICAL STUDIES | FABP1, FABP3, FABP2 | RAB9A 2495/4885MEN1 3427/4885KMT2A 4823/4885 |
| US-20060234206-A1 | Fluorescent probes for biological studies | FABP1, FABP3, FABP2 | RAB9A 2495/4885MEN1 3427/4885KMT2A 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.