SCHEMBL4164569

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4173601	0.86	CDK2 (0.80)	CDK2CDK9CCNT1CDK1CDK4
	SCHEMBL2086282	0.84	CDK2 (0.56)	CDK2CDK9CCNT1CDK1AURKA
	SCHEMBL2074496	0.83	CDK2 (0.67)	CDK2CDK9CCNT1CDK1CDK4
	SCHEMBL4377112	0.82	CDK1 (0.61)	CDK2CDK1JAK2MAPK8MAPK9
	SCHEMBL4168106	0.82	CDK2 (0.69)	CDK2CDK9CCNT1CDK1CDK4
	SCHEMBL3458402	0.81	JAK2 (0.56)	CDK2CDK9CCNT1CDK1CCNE1
	SCHEMBL12423192	0.80	CDK2 (0.53)	CDK2CDK9CCNT1CDK1CCNE1
	SCHEMBL4160812	0.79	CDK2 (0.64)	CDK2CDK9CCNT1CDK1CDK4
	SCHEMBL4173598	0.79	CDK2 (0.62)	CDK2CDK9CCNT1CDK1CDK4
	SCHEMBL4170730	0.78	CDK2 (0.61)	CDK2CDK9CCNT1CDK1CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.