SCHEMBL4165282

SCHEMBL4165282

CCNC(=O)C#CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.38
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
KMT2A Q03164 2/20 0.34
KDM4A O75164 1/20 0.33
FAAH O00519 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
EPHX2 P34913 1/20 0.31
FFAR3 O14843 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
EPHX1 P07099 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22661435 0.89 MCL1 (0.44) MCL1MMP1MMP2MMP3MMP9
SCHEMBL4160606 0.79 EPHX1 (0.48) MMP1MMP2EPHX1
SCHEMBL8439782 0.77
SCHEMBL8950826 0.75
SCHEMBL8950812 0.75
SCHEMBL11754508 0.75
SCHEMBL20488952 0.71
SCHEMBL1750112 0.70
SCHEMBL4150721 0.70
SCHEMBL7794202 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090247680-A1 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2009-10-01 US disclosed
EP-2024440-A2 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2009-02-18 EP disclosed
WO-2007146603-A2 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2007-12-21 WO disclosed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP disclosed
US-4533575-A ETHYLENICALLY UNSATURATED POLYSILOXANE AND POLYHYDROSILOXANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-08-06 US disclosed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP disclosed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US disclosed