⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10579425 | 0.82 | GAA (0.47) | — | |
| SCHEMBL453213 | 0.81 | — | — | |
| SCHEMBL9479682 | 0.79 | GAA (0.44) | — | |
| SCHEMBL17799 | 0.78 | — | — | |
| SCHEMBL17201196 | 0.78 | — | — | |
| SCHEMBL2097722 | 0.77 | GAA (0.43) | — | |
| SCHEMBL244807 | 0.76 | GAA (0.50) | — | |
| Hydrochloric Acid SCHEMBL7501190 | 0.76 | GAA (0.50) | — | |
| Hydrochloric Acid SCHEMBL244808 | 0.76 | GAA (0.50) | — | |
| SCHEMBL2643692 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102333445-A | Method for improving the utilization of the production potential of transgenic plants | BAYER CROPSCIENCE AG | 2012-01-25 | — | — | CN | claimed |
| US-20090118286-A1 | Heterobicyclic Acrylamides | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | US | claimed |
| CN-101171255-A | Heterobicyclic acrylamides | BAYER CROPSCIENCE AG (DE) | 2008-04-30 | — | — | CN | claimed |
| EP-1858899-A1 | HETEROBICYCLIC ACRYLAMIDES | Bayer CropScience AG (DE) | 2007-11-28 | — | — | EP | claimed |
| WO-2006094666-A1 | HETEROBICYCLIC ACRYLAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-09-14 | — | — | WO | claimed |
| CN-111004218-B | Pyrimidine compound containing piperidine and application thereof | 沈阳中化农药化工研发有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-109776427-B | Pyrimidine diamine compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-106279040-B | Pyrimidine compound containing oximino and application thereof | 沈阳中化农药化工研发有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-20200179361-A1 | COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT | TORREY PINES INST FOR MOLECULAR STUDIES (US) | 2020-06-11 | — | — | US | disclosed |
| CN-107074779-B | Pyridazine compounds | 住友化学株式会社 | 2020-05-01 | — | — | CN | disclosed |
| CN-111004218-A | Piperidine-containing pyrimidine compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-04-14 | — | — | CN | disclosed |
| CN-107074781-B | Pyrimidinone compounds | 住友化学株式会社 | 2020-01-17 | — | — | CN | disclosed |
| EP-1218371-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001081334-A2 | CYCLIC AMIDINE COMPOUNDS AND THEIR USE AS ALPHA4BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | SUNTORY LIMITED (JP) | 2001-11-01 | — | — | WO | disclosed |
| WO-2001070733-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2001-09-27 | — | — | WO | disclosed |
| EP-0247381-B1 | 5-FLUROROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5047521-A | Anticarcinogenic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |
| US-4053478-A | ARTERIOSCLEROSIS, THROMBOSIS, HYPERTENSION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1977-10-11 | — | — | US | disclosed |
| US-4012412-A | USEFUL IN THE TREATMENT OF HYPERTENSION, ARTERIOSCLEROSIS, AND THROMBOSIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1977-03-15 | — | — | US | disclosed |