Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.50 |
| ▸ | AVPR1A known ✓ | P37288 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31554969 | 1.00 | GAA (0.50) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL17799 | 0.98 | — | — | |
| SCHEMBL7473161 | 0.86 | GAA (0.51) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| Acetonitrile SCHEMBL28834725 | 0.86 | ALDH1A1 (0.49) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| Pyridine SCHEMBL15644026 | 0.84 | GAA (0.46) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL28251850 | 0.84 | GAA (0.42) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| Toluene SCHEMBL28522020 | 0.82 | GAA (0.49) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8572236 | 0.82 | GAA (0.47) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| Butanone SCHEMBL28417897 | 0.81 | ALDH1A1 (0.57) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL244808 | 0.81 | GAA (0.50) | GAAMAPTL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117185991-A | Refining method of 2-chloro-5-chloromethylpyridine | 河北野田农用化学有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116813535-A | Separation and purification process of 2-chloro-5-chloromethylpyridine synthetic liquid | 宁夏瑞泰科技股份有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-118851990-A | Synthesis method of 2-chloro-5-chloromethylpyridine | 宁夏瑞泰科技股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117185991-A | Refining method of 2-chloro-5-chloromethylpyridine | 河北野田农用化学有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116813535-A | Separation and purification process of 2-chloro-5-chloromethylpyridine synthetic liquid | 宁夏瑞泰科技股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116813535-A | Separation and purification process of 2-chloro-5-chloromethylpyridine synthetic liquid | 宁夏瑞泰科技股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-1198803-C | Heterocyclic compounds having effect of activating nicoting acetylchloine alpha 4 beta 2 receptor | FIRST SUNTORY PHARMACEUTICAL L (JP) | 2005-04-27 | — | — | CN | disclosed |
| US-6407248-B1 | INSECTICIDES, MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| CN-1349506-A | Heterocyclic compounds having effect of activating nicoting acetylchloine alpha 4 beta 2 receptor | SUNTORY LTD (JP) | 2002-05-15 | — | — | CN | disclosed |
| US-20020028809-A1 | Heterocyclic compounds having effect of activating a4beta2 nicotinic acetylcholine receptors | SUNTORY LIMITED | 2002-03-07 | — | — | US | disclosed |
| EP-1176141-A1 | HETEROCYCLIC COMPOUNDS HAVING EFFECT OF ACTIVATING NICOTINIC ACETYLCHOLINE $g(a)4$g(b)2 RECEPTOR | SUNTORY LIMITED (JP) | 2002-01-30 | — | — | EP | disclosed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0509559-A2 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| US-4866066-A | Thiomethylpyridine derivatives and their use for eliciting a bronchosecretolytic or mucolytic response | LUDWIG HEUMANN & CO. GMBH (DE) | 1989-09-12 | — | — | US | disclosed |
| US-4810715-A | BRONCHOSECRETOLYTIC, MUCOLYTIC | LUDWIG HEUMANN & CO. GMBH (DE) | 1989-03-07 | — | — | US | disclosed |
| EP-0302389-A2 | Alpha-unsaturated amines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |
| EP-0093252-B1 | THIOMETHYLPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | LUDWIG HEUMANN & CO GMBH (DE) | 1988-03-09 | — | — | EP | disclosed |
| EP-0093252-A2 | Thiomethylpyridine derivatives, process for their preparation and medicaments containing them | LUDWIG HEUMANN & CO GMBH (DE) | 1983-11-09 | — | — | EP | disclosed |
| US-4332944-A | Compositions and use | ZOECON CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028809-A1 | Heterocyclic compounds having effect of activating a4beta2 nicotinic acetylcholine receptors | CHRNA2, CHRNA7, CHRNB2 | GAA 4288/4885AVPR1A 515/4885MAPT 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.