SCHEMBL4167526

SCHEMBL4167526

CC1CN1.[Ar]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL27587535 0.95
SCHEMBL12943155 0.95
SCHEMBL30460641 0.95
SCHEMBL25163 0.95
SCHEMBL10021534 0.95
SCHEMBL3257377 0.90
SCHEMBL30820024 0.90
Hydrochloric Acid SCHEMBL28045283 0.90
Ammonia Solution, Strong SCHEMBL7699331 0.90
SCHEMBL30881928 0.90 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180318473-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2018-11-08 US disclosed
EP-3345632-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES Abraxis BioScience, LLC (US) 2018-07-11 EP disclosed
EP-3345631-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES Abraxis BioScience, LLC (US) 2018-07-11 EP disclosed
EP-1861070-B1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2018-01-17 EP disclosed
US-20170203012-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2017-07-20 US disclosed
CN-105879114-A DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES 阿布拉西斯生物科学公司 2016-08-24 CN disclosed
EP-2896412-A1 Drugs with improved hydrophobicity for incorporation in medical devices Abraxis BioScience, LLC (US) 2015-07-22 EP disclosed
US-20150190556-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2015-07-09 US disclosed
US-20090130163-A1 Drugs With Improved Hydrophobicity For Incorporation in Medical Devices ABRAXIS BIO SCOENCE, INC. (US) 2009-05-21 US disclosed
EP-1861070-A2 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES Abraxis BioScience, Inc. (US) 2007-12-05 EP disclosed
WO-2007059116-A2 GELDANAMYCIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF ABRAXIS BIOSCIENCE, INC. (US) 2007-05-24 WO disclosed
WO-2006089207-A2 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE, INC. (US) 2006-08-24 WO disclosed