Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | RET | P07949 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | STAT6 | P42226 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206914 | 0.76 | MAPT (0.54) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL13913779 | 0.75 | RET (0.71) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11923106 | 0.75 | ALDH1A1 (0.64) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL6265005 | 0.75 | TLR8 (0.64) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL13913676 | 0.75 | RET (0.78) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL19734665 | 0.74 | HPGD (0.51) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7021742 | 0.74 | ADORA1 (0.61) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL13913706 | 0.71 | RET (0.71) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL13914102 | 0.71 | RET (0.71) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11923107 | 0.71 | KDM4E (0.74) | HPGDKDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235011-B1 | SUBSTITUTED PYRROLO[2, 3-B]AND PYRAZOLO[3, 4-B]PYRIDINES FOR USE AS ADENOSINE RECEPTOR LIGANDS | Bayer Pharma AG (DE) | 2012-01-25 | — | — | EP | disclosed |