Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396760 | 0.81 | NOTUM (0.48) | NPY5RNOTUMMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4171141 | 0.81 | CKS1B (0.48) | NOTUMMAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL2448926 | 0.81 | GFER (0.45) | NPY5RNOTUMMAPTL3MBTL1LMNA | |
| SCHEMBL27655935 | 0.79 | SUV39H2 (0.54) | NPY5RNOTUMMAPTSMN1; SMN2RAB9A | |
| SCHEMBL6183399 | 0.76 | NOTUM (0.61) | NPY5RNOTUM | |
| SCHEMBL4171144 | 0.74 | NPY5R (0.56) | NPY5RNOTUMMAPTSMN1; SMN2RAB9A | |
| SCHEMBL4167396 | 0.74 | MAPT (0.56) | NPY5RNOTUMMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2074272 | 0.73 | NOTUM (0.83) | NOTUMMAPTSMN1; SMN2L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL4185135 | 0.73 | MAPT (0.54) | NPY5RNOTUMMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6694923 | 0.72 | NOTUM (0.58) | NOTUMMAPTSMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124663-A1 | Novel n-phenyl-piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2009-05-14 | — | — | US | disclosed |
| EP-1896415-A1 | NOVEL N-PHENYL-PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NeuroSearch A/S (DK) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006131524-A1 | NOVEL N-PHENYL-PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124663-A1 | Novel n-phenyl-piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | SLC18A2, SLC6A2, SLC18A3 | NPY5R 186/4885NOTUM 640/4885MAPT 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.