SCHEMBL4170724

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13852372	0.91	CDK2 (0.77)	CDK2CDK9AURKAAURKBCDK4
	SCHEMBL4165922	0.91	CDK2 (0.79)	CDK2CDK9AURKAAURKBCDK4
	SCHEMBL4162602	0.87	CDK2 (0.73)	CDK2CDK9AURKAAURKBCDK4
	SCHEMBL2073428	0.86	CDK2 (1.00)	CDK2CDK9AURKAAURKBCDK4
	SCHEMBL2075827	0.85	CDK2 (1.00)	CDK2CDK9AURKAAURKBCDK4
	SCHEMBL4160087	0.84	CDK2 (0.71)	CDK2CDK9AURKAAURKBCDK4
	SCHEMBL4154271	0.84	CDK2 (1.00)	CDK2CDK9AURKAAURKBCDK4
	SCHEMBL4158794	0.84	CDK2 (0.73)	CDK2CDK9AURKAAURKBCDK4
	SCHEMBL4158649	0.83	CDK9 (1.00)	CDK2CDK9AURKAAURKBCDK4
	SCHEMBL4173509	0.82	CDK2 (0.71)	CDK2CDK9AURKAAURKBCDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.