Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL28171879 | 0.94 | HCAR2 (0.50) | ALDH1A1HCAR2LMNAAKR1B10AKR1B1 | |
| Acrylic Acid Ethyl Ester SCHEMBL3690840 | 0.93 | ALDH1A1 (0.49) | ALDH1A1HCAR2LMNATHRBTGM2 | |
| SCHEMBL28246245 | 0.93 | ALDH1A1 (0.49) | ALDH1A1HCAR2LMNAAKR1B10AKR1B1 | |
| SCHEMBL28311598 | 0.92 | ALDH1A1 (0.47) | ALDH1A1HCAR2LMNAAKR1B10AKR1B1 | |
| SCHEMBL628109 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HCAR2LMNAAKR1B10AKR1B1 | |
| Acrylic Acid Methyl Ester SCHEMBL27594684 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HCAR2LMNAAKR1B10AKR1B1 | |
| Acrylic Acid Ethyl Ester SCHEMBL28277476 | 0.91 | ALDH1A1 (0.44) | ALDH1A1HCAR2LMNAAKR1B10AKR1B1 | |
| Acrylic Acid SCHEMBL1224596 | 0.91 | ALDH1A1 (0.56) | ALDH1A1HCAR2LMNAAKR1B10AKR1B1 | |
| Methacrylic Acid SCHEMBL6054004 | 0.91 | ALDH1A1 (0.56) | ALDH1A1HCAR2LMNAAKR1B10AKR1B1 | |
| SCHEMBL1395905 | 0.90 | ALDH1A1 (0.46) | ALDH1A1HCAR2LMNAAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | claimed |
| EP-1802726-A4 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LTD (AU) | 2008-04-30 | — | — | EP | claimed |
| EP-1802726-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | Polymers Australia PTY Limited (AU) | 2007-07-04 | — | — | EP | claimed |
| WO-2006024099-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2006-03-09 | — | — | WO | claimed |
| CN-119391032-A | Preparation and application of zwitterionic polymer monomer modified soft hydrophobic acrylate copolymer | 厦门大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-109124826-B | Ophthalmic lens | 爱博诺德(北京)医疗科技股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| EP-0397683-B1 | COMPOSITIONS FOR MAKING IMPROVED GAS PERMEABLE CONTACT LENSES | FUSED KONTACTS OF CHICAGO INC (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0397683-A4 | COMPOSITIONS FOR MAKING IMPROVED GAS PERMEABLE CONTACT LENSES | — | 1991-01-30 | — | — | EP | disclosed |
| EP-0397683-A1 | COMPOSITIONS FOR MAKING IMPROVED GAS PERMEABLE CONTACT LENSES. | FUSED KONTACTS OF CHICAGO INC (US) | 1990-11-22 | — | — | EP | disclosed |
| WO-1990002144-A1 | COMPOSITIONS FOR MAKING IMPROVED GAS PERMEABLE CONTACT LENSES | FUSED KONTACTS OF CHICAGO, INC. (US) | 1990-03-08 | — | — | WO | disclosed |
| US-4766189-A | POLYMER FROM UNSATURATED SILICATE, LOWER ALKYL ESTER SILOXANE, ACRYLIC ESTER, FLUOROACRYLIC ESTER AND WETTING AGENT | FUSED KONTACTS OF CHICAGO, INC. (US) | 1988-08-23 | — | — | US | disclosed |