SCHEMBL4170813

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4173628	0.89	PDE10A (0.43)	PDE10ATTBK1TTBK2CSNK1A1CSNK1D
	SCHEMBL4170611	0.88	PDE10A (0.48)	PDE10ATTBK1TTBK2CSNK1A1CSNK1D
	SCHEMBL4172140	0.87	KDR (0.43)	PDE10ACSNK1A1CSNK1DCBFBLMNA
	SCHEMBL4173611	0.81	CSNK1D (0.52)	PDE10ATTBK1TTBK2CSNK1A1CSNK1D
	SCHEMBL4164550	0.78	CSNK1A1 (0.59)	PDE10ATTBK1TTBK2CSNK1A1CSNK1D
	SCHEMBL4173092	0.78	CSNK1D (0.48)	PDE10ATTBK1TTBK2CSNK1A1CSNK1D
	SCHEMBL4161807	0.76	KDR (0.52)	PDE10ACSNK1A1CSNK1DP2RX3TEK
	SCHEMBL4170478	0.76	PDE10A (0.52)	PDE10ATTBK1TTBK2CSNK1A1CSNK1D
	SCHEMBL4166878	0.75	MGAM (0.49)	PDE10ACSNK1A1CSNK1DALDH1A1NPC1
	SCHEMBL4161663	0.74	CACNA1H (0.52)	PDE10ATTBK1TTBK2CSNK1A1CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.