SCHEMBL4173628

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4170813	0.89	PDE10A (0.45)	PDE10AALDH1A1HTTTDP1TTBK1
	SCHEMBL4161807	0.88	KDR (0.52)	PDE10AKDRCSNK1A1CSNK1DP2RX3
	SCHEMBL4170611	0.84	PDE10A (0.48)	PDE10AALDH1A1HTTTDP1TTBK1
	SCHEMBL4173092	0.80	CSNK1D (0.48)	PDE10AALDH1A1HTTTDP1TTBK1
	SCHEMBL4164725	0.79	CSNK1A1 (0.52)	PDE10AALDH1A1HTTTDP1TTBK1
	SCHEMBL4172506	0.78	KDR (0.48)	PDE10AALDH1A1HTTTDP1TTBK1
	SCHEMBL4170478	0.78	PDE10A (0.52)	PDE10AALDH1A1HTTTDP1TTBK1
	SCHEMBL4173611	0.77	CSNK1D (0.52)	PDE10AALDH1A1TTBK1TTBK2KDR
	SCHEMBL4172140	0.76	KDR (0.43)	PDE10AKDRCSNK1A1CSNK1DRAF1
	SCHEMBL4164550	0.76	CSNK1A1 (0.59)	PDE10AHTTTTBK1TTBK2KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.