SCHEMBL417152

SCHEMBL417152

O=S(=O)(Cl)N1CCCCC1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
POLB P06746 2/20 0.58
TSHR P16473 6/20 0.55
KMT2A Q03164 2/20 0.55
USP2 O75604 1/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
FKBP1A P62942 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
ALOX15 P16050 1/20 0.39
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3937944 1.00 CA1 (0.58) CA1CA2POLBTSHRKMT2A
SCHEMBL745037 0.97
SCHEMBL1935164 0.90
SCHEMBL22003894 0.82
SCHEMBL2261416 0.82 POLB (0.42) CA1CA2POLBTSHRKMT2A
SCHEMBL5280013 0.76 POLB (0.93) CA1CA2POLBTSHRKMT2A
SCHEMBL29905605 0.76 POLB (0.93) CA1CA2POLBTSHRKMT2A
SCHEMBL9540497 0.73 CA1 (0.58) CA1CA2POLBTSHRKMT2A
SCHEMBL21356989 0.73 CA1 (1.00) CA1CA2POLBTSHRKMT2A
SCHEMBL392889 0.73 CA1 (1.00) CA1CA2POLBTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059400-A Copper-clad plate with high adhesive force and manufacturing method thereof 江门建滔电子发展有限公司 2025-05-30 CN claimed
CN-119081574-A Flame-retardant PET (polyethylene terephthalate) adhesive tape and preparation method thereof 常州市白鹭电器有限公司 2024-12-06 CN claimed
EP-3077373-B1 PREPARATION OF COBICISTAT INTERMEDIATES MYLAN LABORATORIES LTD (IN) 2018-09-12 EP claimed
US-20160297780-A1 Preparation of Cobicistat Intermediates Mylan Laboratories Ltd. (IN) 2016-10-13 US claimed
EP-3077373-A1 PREPARATION OF COBICISTAT INTERMEDIATES Mylan Laboratories Ltd. (IN) 2016-10-12 EP claimed
WO-2015083066-A1 PREPARATION OF COBICISTAT INTERMEDIATES Mylan Laboratories Ltd. (IN) 2015-06-11 WO claimed
US-12600711-B2 Triazacyclododecansulfonamide (TCD)-based protein secretion inhibitors KEZAR LIFE SCIENCES, INC. (US) 2026-04-14 US disclosed
EP-3941919-B1 PYRIDO-PYRIMIDINONE AND PTERIDINONE COMPOUNDS AS INHIBITORS OF ENDORIBONUCLEASE INOSITOL REQUIRING ENZYME I (IRE I ALPHA) FOR THE TREATMENT OF CANCER DISEASES. GENENTECH INC (US) 2025-12-24 EP disclosed
US-12486253-B2 Therapeutics for the degradation of mutant BRAF C4 THERAPEUTICS, INC. (US) 2025-12-02 US disclosed
US-12344603-B2 Pyrido-pyrimidinone and pteridinone compounds and methods of use GENENTECH, INC. (US) 2025-07-01 US disclosed
CN-120192251-A Sulfonamide compound for resisting prostate cancer and application thereof 浙江大学 2025-06-24 CN disclosed
EP-3728194-B1 QUINOLINE SULFONAMIDE COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS OTAGO INNOVATION LTD (NZ) 2025-06-04 EP disclosed
CN-120059400-A Copper-clad plate with high adhesive force and manufacturing method thereof 江门建滔电子发展有限公司 2025-05-30 CN disclosed
US-4148659-A NONSILVER PHOTOGRAPHY AGFA-GEVAERT N.V. (BE) 1979-04-10 US disclosed
US-4075351-A INHIBITION OF MALE FERTILITY WITH ALIPHATIC SULFAMATES ORTHO PHARMACEUTICAL CORPORATION (US) 1978-02-21 US disclosed
US-4066778-A ANTIBACTERIAL, ANTIPROTAZOA, ANTHELMINTIC CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed
US-3997585-A Aliphatic sulfamates ORTHO PHARMACEUTICAL CORPORATION (US) 1976-12-14 US disclosed
US-3976778-A ANTHELMINTIC, BACTERICIDE, ANTIPROTOZOA CIBA-GEIGY CORPORATION (US) 1976-08-24 US disclosed
US-3951959-A VAGINOTROPIC SCHERING AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed
US-3951958-A VAGINOTROPIC SCHERING AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486253-B2 Therapeutics for the degradation of mutant BRAF BRAF, NRAS, KRAS CA1 4783/4885CA2 4314/4885POLB 1018/4885
US-20160297780-A1 Preparation of Cobicistat Intermediates PARP8, PARP9, PRSS8 CA1 2959/4885CA2 2741/4885POLB 844/4885
US-12600711-B2 Triazacyclododecansulfonamide (TCD)-based protein secretion inhibitors CD274, CD40, ICOS CA1 4823/4885CA2 3864/4885POLB 4585/4885
US-12344603-B2 Pyrido-pyrimidinone and pteridinone compounds and methods of use TYMP, TYMS, DPYD CA1 4838/4885CA2 4297/4885POLB 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.