⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225809 | 1.00 | — | — | |
| SCHEMBL2888206 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28802865 | 0.97 | ROCK2 (0.53) | — | |
| Hydrochloric Acid SCHEMBL14759581 | 0.97 | ROCK2 (0.53) | — | |
| Hydrochloric Acid SCHEMBL6432778 | 0.97 | ROCK2 (0.53) | — | |
| Hydrochloric Acid SCHEMBL2750606 | 0.97 | ROCK2 (0.53) | — | |
| Hydrochloric Acid SCHEMBL1002182 | 0.97 | ROCK2 (0.53) | — | |
| SCHEMBL8221139 | 0.85 | ROCK2 (0.50) | — | |
| SCHEMBL9931515 | 0.85 | ROCK2 (0.50) | — | |
| SCHEMBL21877119 | 0.85 | ROCK2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431312-A | Enzymatic serum albumin fluorescent probe and synthesis and application thereof | 河北大学 | 2025-02-14 | — | — | CN | claimed |
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | claimed |
| CN-109311850-B | Imidazolone compounds as human neutrophil elastase inhibitors | 奇斯药制品公司 | 2021-11-19 | — | — | CN | claimed |
| EP-3464273-B9 | IMIDAZOLONE COMPOUNDS AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | CHIESI FARM SPA (IT) | 2020-10-21 | — | — | EP | claimed |
| EP-3464273-B1 | IMIDAZOLONE COMPOUNDS AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | CHIESI FARM SPA (IT) | 2020-04-08 | — | — | EP | claimed |
| CN-109311850-A | Imidazoquinolone compounds as people's inhibitors of neutrophil elastase | 奇斯药制品公司 | 2019-02-05 | — | — | CN | claimed |
| US-20180009787-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-01-11 | — | — | US | claimed |
| US-9802919-B1 | Compounds | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-10-31 | — | — | US | claimed |
| US-12527779-B2 | Prostaglandin E2 (PGE2) EP4 receptor antagonists | DOMAIN THERAPEUTICS (FR) | 2026-01-20 | — | — | US | disclosed |
| CN-119431312-B | Enzymatic serum albumin fluorescent probe and synthesis and application thereof | 河北大学 | 2025-09-26 | — | — | CN | disclosed |
| CN-119431312-A | Enzymatic serum albumin fluorescent probe and synthesis and application thereof | 河北大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-119431225-A | Dion-Jacobson two-dimensional organic-inorganic hybrid chiral perovskite single crystal and preparation method and application thereof | 河南大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-119431312-A | Enzymatic serum albumin fluorescent probe and synthesis and application thereof | 河北大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | disclosed |
| US-20050107419-A1 | Condensed heterocyclic compounds as calcitonin agonists | SMITHKLINE BEECHAM CORPORATION | 2005-05-19 | — | — | US | disclosed |
| EP-1320540-A2 | PEPTIDOMIMETIC PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-06-25 | — | — | EP | disclosed |
| US-6420398-B2 | FOR TREATING AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS; 4-(3-(2-(ACETYLTHIO)ETHYL)-3-(2-CYCLOHEXYLETHYL)-UREIDOMETHYL)-1 -METHYLPYRIDINIUM IODIDE, FOR EXAMPLE; INHIBIT PRODUCTION OF TUMOR NECROSIS FACTOR ALPHA (TNF-A) | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| WO-2002018369-A2 | PEPTIDOMIMETIC PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |
| US-20010041725-A1 | Novel urea derivatives having nitrogen aromatic heterocycle | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-1103543-A1 | NOVEL UREA DERIVATIVES BEARING NITROGENOUS AROMATIC HETEROCYCLES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-05-30 | — | — | EP | disclosed |