SCHEMBL4171841

SCHEMBL4171841

O=C(O)C#CC(C(=O)O)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
LMNA P02545 1/20 0.30
ALDH1A1 P00352 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705238 0.78
SCHEMBL27529857 0.71
SCHEMBL7209893 0.71 SLC7A5 (0.38) ALDH1A1
SCHEMBL16670899 0.71 TP53 (0.38)
SCHEMBL28410797 0.71
SCHEMBL27854671 0.69
SCHEMBL1444571 0.69
SCHEMBL28403500 0.67
SCHEMBL15145733 0.67
Hydrochloric Acid SCHEMBL10660012 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1224165-B1 NOVEL COMPOUNDS NEW PHARMA RES SWEDEN AB (SE) 2005-12-14 EP claimed
US-20090247680-A1 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2009-10-01 US disclosed
EP-2024440-A2 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2009-02-18 EP disclosed
WO-2007146603-A2 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2007-12-21 WO disclosed
EP-0391163-B1 Adherent silicone coating GEN ELECTRIC (US) 1995-03-08 EP disclosed
US-5082871-A Acetylenedicarboxylate gelation inhibitor GENERAL ELECTRIC COMPANY (US) 1992-01-21 US disclosed
EP-0391163-A2 Adherent silicone coating GENERAL ELECTRIC COMPANY (US) 1990-10-10 EP disclosed
US-4943601-A Coating with improved adhesion GENERAL ELECTRIC COMPANY (US) 1990-07-24 US disclosed
US-4347346-A DIALKYLACETYLENEDICARBOXYITE TO PREVENT PREMATURE GELATION GENERAL ELECTRIC COMPANY (US) 1982-08-31 US disclosed
US-4340710-A ETHYLENICALLY UNSATURATED ISOCYANURATE AND DIALKYL ACETYLENEDICARBOXYLATE STABILIZERS TO INHIBIT PREMATURE GELATION GENERAL ELECTRIC COMPANY (US) 1982-07-20 US disclosed