Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548436 | 0.81 | SLC7A5 (0.36) | SLC7A5PTGS1ALDH1A1MAPTSLC1A3 | |
| SCHEMBL6777078 | 0.78 | — | — | |
| SCHEMBL27257158 | 0.77 | SLC7A5 (0.33) | SLC7A5PTGS1ALDH1A1MAPT | |
| SCHEMBL27854671 | 0.77 | — | — | |
| SCHEMBL23699031 | 0.74 | — | — | |
| SCHEMBL27257226 | 0.74 | SLC7A5 (0.31) | SLC7A5 | |
| SCHEMBL16670899 | 0.72 | TP53 (0.38) | SLC7A5TP53 | |
| SCHEMBL5201370 | 0.72 | — | — | |
| SCHEMBL4171841 | 0.71 | TSHR (0.30) | ALDH1A1 | |
| SCHEMBL1444571 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874846-B1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2003-04-02 | — | — | EP | claimed |