Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176822 | 0.95 | ABCB1 (1.00) | ABCB1DRD2 | |
| SCHEMBL4182261 | 0.94 | ABCB1 (1.00) | ABCB1DRD2 | |
| SCHEMBL4181085 | 0.87 | ABCB1 (1.00) | ABCB1DRD2 | |
| SCHEMBL4183345 | 0.86 | ABCB1 (1.00) | ABCB1DRD2 | |
| SCHEMBL4186798 | 0.86 | ABCB1 (1.00) | ABCB1DRD2 | |
| SCHEMBL4179477 | 0.82 | ABCB1 (1.00) | ABCB1DRD2 | |
| SCHEMBL4186793 | 0.82 | ABCB1 (1.00) | ABCB1DRD2 | |
| SCHEMBL4180271 | 0.81 | ABCB1 (1.00) | ABCB1DRD2 | |
| SCHEMBL4189432 | 0.81 | ABCB1 (1.00) | ABCB1DRD2 | |
| SCHEMBL4168989 | 0.81 | ABCB1 (1.00) | ABCB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093493-A1 | 1-PHENYLALCOXY-2-BETA-PHENYLETHYL DERIVATIVES AS P-GLYCOPROTEIN (P-GP) INHIBITORS USEFUL IN DRUG RESISTANCE EVENTS | UNIVERSITA DI PISA, 40% (IT) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093493-A1 | 1-PHENYLALCOXY-2-BETA-PHENYLETHYL DERIVATIVES AS P-GLYCOPROTEIN (P-GP) INHIBITORS USEFUL IN DRUG RESISTANCE EVENTS | ABCB1, ABCC1, ABCC2 | ABCB1 1/4885DRD2 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.