Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172390 | 1.00 | MCHR1 (0.40) | MCHR1POLBNPC1RAB9ARXFP1 | |
| SCHEMBL13852007 | 0.94 | MCHR1 (0.37) | MCHR1POLBNPC1RAB9ARXFP1 | |
| SCHEMBL13852006 | 0.90 | GSK3A (0.36) | MCHR1SMN1; SMN2CCR3KMT2A | |
| SCHEMBL13852011 | 0.88 | MCHR1 (0.40) | MCHR1POLBNPC1RAB9ARXFP1 | |
| SCHEMBL13852013 | 0.87 | MCHR1 (0.41) | MCHR1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13852009 | 0.85 | MCHR1 (0.42) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL83172 | 0.82 | MCHR1 (0.44) | MCHR1POLBSMN1; SMN2PROKR1EBP | |
| SCHEMBL13852012 | 0.81 | MCHR1 (0.39) | MCHR1POLBSMN1; SMN2PROKR1EBP | |
| SCHEMBL74317 | 0.80 | CCR3 (0.44) | MCHR1CCR3KMT2A | |
| SCHEMBL74318 | 0.80 | CCR3 (0.44) | MCHR1CCR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179921-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140179921-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140179921-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-26 | — | — | US | disclosed |
| US-20130197029-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130197029-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130197029-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-01 | — | — | US | disclosed |
| US-8338443-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338443-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338443-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC (US) | 2009-05-07 | — | — | US | disclosed |
| EP-1965651-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007072143-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007072143-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197029-A1 | CHEMICAL COMPOUNDS | MRM1, H1-0, RO60 | MCHR1 831/4885POLB 3887/4885NPC1 1577/4885 |
| US-20140179921-A1 | CHEMICAL COMPOUNDS | H1-0, REL, ZYX | MCHR1 1623/4885POLB 1718/4885NPC1 1914/4885 |
| US-20090118295-A1 | CHEMICAL COMPOUNDS | MRM1, MNS1, CHRM1 | MCHR1 745/4885POLB 3986/4885NPC1 1763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.