Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12449306 | 0.78 | NSD2 (0.63) | NSD2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL16429673 | 0.77 | NSD2 (0.62) | NSD2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL4148674 | 0.75 | NSD2 (0.60) | NSD2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL8486414 | 0.75 | NSD2 (0.59) | NSD2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11873216 | 0.73 | NSD2 (0.57) | NSD2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL13852997 | 0.72 | NSD2 (0.56) | NSD2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11784089 | 0.72 | NSD2 (0.55) | NSD2KMT2AMEN1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11786823 | 0.71 | NSD2 (0.54) | NSD2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL14958998 | 0.70 | MAPT (0.53) | NSD2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL12258293 | 0.70 | KMT2A (0.61) | NSD2KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617255-B2 | Organic electroluminescent element, and illumination device and display device each comprising the element | Konica Minolta, Inc. (JP) | 2017-04-11 | — | — | US | disclosed |
| US-9193869-B2 | Dye compounds, method of making the compounds and ink composition employing the compounds | XEROX CORPORATION (US) | 2015-11-24 | — | — | US | disclosed |
| US-20150057394-A1 | DYE COMPOUNDS, METHOD OF MAKING THE COMPOUNDS AND INK COMPOSITION EMPLOYING THE COMPOUNDS | XEROX CORPORATION (US) | 2015-02-26 | — | — | US | disclosed |
| US-8852757-B2 | Organic electroluminescence element, lighting device and display device | KONICA MINOLTA HOLDINGS, INC. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-8852757-B2 | Organic electroluminescence element, lighting device and display device | KONICA MINOLTA HOLDINGS, INC. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-8710088-B2 | Pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2014-04-29 | — | — | US | disclosed |
| US-8710088-B2 | Pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2014-04-29 | — | — | US | disclosed |
| US-8710088-B2 | Pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2014-04-29 | — | — | US | disclosed |
| US-8541488-B2 | Formed resin article and polymer film | FUJIFILM CORPORATION (JP) | 2013-09-24 | — | — | US | disclosed |
| US-8541488-B2 | Formed resin article and polymer film | FUJIFILM CORPORATION (JP) | 2013-09-24 | — | — | US | disclosed |
| US-20100004439-A1 | Heterocyclic Compound | FUJIFLM CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20100004439-A1 | Heterocyclic Compound | FUJIFLM CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20090239982-A1 | Ultraviolet Absorbent and Heterocyclic Compound | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090239982-A1 | Ultraviolet Absorbent and Heterocyclic Compound | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090117040-A1 | Novel pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases | MAX-DELBRUG-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20090117040-A1 | Novel pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases | MAX-DELBRUG-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20090117040-A1 | Novel pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases | MAX-DELBRUG-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2009-05-07 | — | — | US | disclosed |
| EP-0406812-B1 | Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine | HERCULES INC (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5097029-A | Hydrolysis, alkylation, intermediates for azo dyes | HERCULES INCORPORATED (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0406812-A2 | Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine | HERCULES INCORPORATED (US) | 1991-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239982-A1 | Ultraviolet Absorbent and Heterocyclic Compound | CYP2A6, CYP2B6, XPO6 | NSD2 4354/4885KMT2A 2903/4885MEN1 1907/4885 |
| US-20090117040-A1 | Novel pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases | APP, PSEN2, PSEN1 | NSD2 4678/4885KMT2A 4715/4885MEN1 1020/4885 |
| US-20100004439-A1 | Heterocyclic Compound | PTGER1, CYP1A1, ALOX12 | NSD2 1105/4885KMT2A 2188/4885MEN1 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.