Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177593 | 0.79 | KCNN4 (0.52) | KCNN4TAAR1MAPK1MAPTKMT2A | |
| SCHEMBL1244641 | 0.78 | KCNN4 (0.50) | KCNN4TAAR1MAPK1MAPTKMT2A | |
| SCHEMBL16039033 | 0.74 | KCNN4 (0.52) | KCNN4TAAR1MAPK1MAPTKMT2A | |
| SCHEMBL29061572 | 0.74 | KCNN4 (0.52) | KCNN4TAAR1MAPK1MAPTKMT2A | |
| SCHEMBL622821 | 0.74 | KCNN4 (0.52) | KCNN4TAAR1MAPK1MAPTKMT2A | |
| SCHEMBL295112 | 0.73 | MAPK1 (0.50) | KCNN4TAAR1MAPK1MAPTKMT2A | |
| SCHEMBL9516748 | 0.73 | MAPK1 (0.50) | KCNN4TAAR1MAPK1MAPTKMT2A | |
| SCHEMBL708445 | 0.73 | KCNN4 (0.58) | KCNN4TAAR1MAPK1MAPTKMT2A | |
| SCHEMBL6145 | 0.73 | KCNN4 (0.58) | KCNN4TAAR1MAPK1MAPTKMT2A | |
| SCHEMBL3256578 | 0.73 | KCNN4 (0.58) | KCNN4TAAR1MAPK1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146784-B | Thiazole derivatives as PPAR delta ligands and manufacturing process thereof | SEOUL NAT UNIV IND FOUNDATION (KR) | 2012-09-05 | — | — | CN | disclosed |
| US-20090054493-A1 | THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS | Kang, Heonjoong Kang (KR) | 2009-02-26 | — | — | US | disclosed |
| CN-101146784-A | Thiazole derivatives as PPAR delta ligands and manufacturing process thereof | KANG HEONJOONG (KR) | 2008-03-19 | — | — | CN | disclosed |
| EP-1856072-A1 | THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS | Kang, Heonjoong (KR) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006091047-A1 | THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS | KANG HEONJOONG (KR) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054493-A1 | THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS | PPARD, PPARG, PPARA | KCNN4 4876/4885TAAR1 1529/4885MAPK1 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.