Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177593 | 0.82 | KCNN4 (0.52) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL295112 | 0.81 | MAPK1 (0.50) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL9516748 | 0.81 | MAPK1 (0.50) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL4173059 | 0.78 | KCNN4 (0.48) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL20558768 | 0.78 | LTA4H (0.52) | MAPK1ALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL11637695 | 0.77 | TSHR (0.52) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL7499577 | 0.77 | ALDH1A1 (0.52) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL1253796 | 0.77 | ALDH1A1 (0.48) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL3256578 | 0.75 | KCNN4 (0.58) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL1514215 | 0.75 | MAPK1 (0.50) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104672359-B | A kind of method that vinylic polar monomer implements anionic addition polymerization | 华东理工大学 | 2017-03-15 | — | — | CN | claimed |
| CN-105073889-A | Composition of reinforced polyalkylene terephthalate, preparation and use thereof | BASF SE | 2015-11-18 | — | — | CN | claimed |
| CN-104672359-A | Method for carrying out anionic addition polymerization on polar vinyl monomer | UNIV EAST CHINA SCIENCE & TECH | 2015-06-03 | — | — | CN | claimed |
| US-8546503-B2 | Method for controlling anionic polymerization | East China University Of Science And Technology; Shanghai Fuen Plast-Rubber Corporation Of Science And Technology (CN) | 2013-10-01 | — | — | US | claimed |
| US-20120116023-A1 | METHOD FOR CONTROLLING ANIONIC POLYMERIZATION | SHANGHAI FUEN PLAST-RUBBER CORPORATION OF SCIENCE AND TECHNOLOGY (CN) | 2012-05-10 | — | — | US | claimed |
| CN-102093192-A | Beta-diketone 1-(3,5-dibenzyloxy)phenyl-5-phenylacetylacetone and preparation method thereof | UNIV NORTH CHINA | 2011-06-15 | — | — | CN | claimed |
| US-7928134-B2 | 5-aryl-4,5-dihydro-(1H)-pyrazolines as cannabinoid CB1 receptor agonists | SOLVAY PHARMACEUTICALS B.V. (NL) | 2011-04-19 | — | — | US | claimed |
| EP-2203427-A2 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLES AS CANNABINOID CB1 RECEPTOR AGONISTS | Abbott Healthcare Products B.V. (NL) | 2010-07-07 | — | — | EP | claimed |
| WO-2009037244-A2 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLES AS CANNABINOID CB1 RECEPTOR AGONISTS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2009-03-26 | — | — | WO | claimed |
| US-20090082396-A1 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLINES AS CANNABINOID CB1 RECEPTOR AGONISTS | SOLVAY PHARMACEUTICALS B.V. | 2009-03-26 | — | — | US | claimed |
| EP-1046642-B1 | Process for preparation of silyl-bridged fluorenyl-cyclopentadienyl ligands and silyl-bridged fluorenyl-cyclopentadienyl metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2004-06-30 | — | — | EP | claimed |
| US-6346635-B1 | FORMING A COMPLEX, DEPROTINATION, SILATION AND COMPLEXING | BASELL POLYOLEFINE GMBH (DE) | 2002-02-12 | — | — | US | claimed |
| EP-1046642-A2 | Process for preparation of silyl-bridged fluorenyl-cyclopentadienyl ligands and silyl-bridged fluorenyl-cyclopentadienyl metallocenes | TARGOR GmbH (DE) | 2000-10-25 | — | — | EP | claimed |
| EP-0400478-A2 | Branched polycarbonates and method of preparation | GENERAL ELECTRIC COMPANY (US) | 1990-12-05 | — | — | EP | claimed |
| EP-0134041-B1 | N-CHLOROCARBONYLOXY-5-NORBORNENE-2,3-DICARBOXIMIDE, PROCESS FOR ITS PREPARATION AND ITS USE | Akademie der Wissenschaften der DDR (DE) | 1988-04-06 | — | — | EP | claimed |
| EP-0134041-A1 | N-Chlorocarbonyloxy-5-norbornene-2,3-dicarboximide, process for its preparation and its use | Akademie der Wissenschaften der DDR (DE) | 1985-03-13 | — | — | EP | claimed |
| US-4419490-A | GROUP 8 METAL | HEYL & CO. CHEMISCH-PHARMAZEUTISCHE FABRIK (DE) | 1983-12-06 | — | — | US | claimed |
| CN-117845289-A | Copper electroplating bath containing the reaction product of an amine, a polyacrylamide and a diepoxide | 罗门哈斯电子材料有限责任公司 | 2024-04-09 | — | — | CN | disclosed |
| US-4412001-A | IMMOBILIZATION BY BINDING TO A LIGAND-SPACER-SUPPORT; WASHING; DESORPTION; PURIFICATION | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1983-10-25 | — | — | US | disclosed |
| EP-0057600-A2 | Affinity resins and their use in isolating bacterial luciferase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1982-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082396-A1 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLINES AS CANNABINOID CB1 RECEPTOR AGONISTS | CNR1, CNR2, HTR5A | KCNN4 996/4885MAPK1 1457/4885ALDH1A1 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.