⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27073603 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL11232014 | 0.97 | — | — | |
| SCHEMBL1188226 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL10909301 | 0.78 | — | — | |
| SCHEMBL11191939 | 0.78 | — | — | |
| SCHEMBL10674882 | 0.77 | — | — | |
| SCHEMBL10947166 | 0.74 | — | — | |
| SCHEMBL10620287 | 0.74 | — | — | |
| SCHEMBL3976946 | 0.74 | — | — | |
| SCHEMBL6931903 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023942-A1 | Method for Producing Bi-Functional Ammonium Nitriles | CLARIANT PRODUKTE (DEUTSCHALND) GMBH (DE) | 2009-01-22 | — | — | US | claimed |
| EP-1856034-A1 | METHOD FOR PRODUCING BIFUNCTIONAL AMMONIUM NITRILES | Clariant Produkte (Deutschland) GmbH (DE) | 2007-11-21 | — | — | EP | claimed |
| WO-2006092247-A1 | METHOD FOR PRODUCING BIFUNCTIONAL AMMONIUM NITRILES | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2006-09-08 | — | — | WO | claimed |
| EP-1215196-B1 | Selective reductive amination of nitriles | AIR PROD & CHEM (US) | 2004-05-12 | — | — | EP | claimed |
| EP-0913388-B1 | Hydrogenation of nitriles to produce amines | AIR PROD & CHEM (US) | 2003-10-01 | — | — | EP | claimed |
| EP-1094058-B1 | Selective reductive amination of nitriles | AIR PROD & CHEM (US) | 2003-09-03 | — | — | EP | claimed |
| EP-1215196-A1 | Selective reductive amination of nitriles | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-06-19 | — | — | EP | claimed |
| US-6248925-B1 | REACTING A NITRILE WITH A PRIMARY OR SECONDARY AMINE EFFECTING CONVERSION OF THE NITRILE GROUP TO THE CORRESPONDING SECONDARY OR TERTIARY AMINE; PROMOTIONALLY EFFECTIVE AMOUNT OF A LITHIUM COMPOUND OR SODIUM CHLORIDE. | AIR PRODUCTS AND CHEMICALS, INC. | 2001-06-19 | — | — | US | claimed |
| EP-1094058-A1 | Selective reductive amination of nitriles | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-04-25 | — | — | EP | claimed |
| EP-0913388-A1 | Hydrogenation of nitriles to produce amines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-05-06 | — | — | EP | claimed |
| US-5869653-A | USING SPONGE OR RANEY COBALT CATALYST; AMMONIA-FREE REACTION | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-02-09 | — | — | US | claimed |
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |
| WO-2021212039-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-10-21 | — | — | WO | disclosed |
| US-10226449-B2 | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V BIOSCIENCES, INC. (US) | 2019-03-12 | — | — | US | disclosed |
| US-20180222892-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. | 2018-08-09 | — | — | US | disclosed |
| US-4382090-A | N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| US-4375547-A | ANTIHISTAMINES, 'I RECEPTOR ANTAGONISTS, ANTISECRETORY AGENTS | ELI LILLY AND COMPANY (US) | 1983-03-01 | — | — | US | disclosed |
| EP-0050890-A1 | Stabilized compositions of chlorinated solvents | SOLVAY & Cie (Société Anonyme) (BE) | 1982-05-05 | — | — | EP | disclosed |
| EP-0049618-A1 | Improvements in or relating to 2,4-disubstituted thiazole derivatives | ELI LILLY AND COMPANY (US) | 1982-04-14 | — | — | EP | disclosed |
| EP-0044111-A1 | Stabilised 1,1,1-trichloro-ethane compositions | SOLVAY & Cie (Société Anonyme) (BE) | 1982-01-20 | — | — | EP | disclosed |