Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.74 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.74 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691910 | 1.00 | PTGER4 (0.74) | PTGER4PTGER2MRGPRX4PTGER1PTGDR | |
| SCHEMBL692039 | 0.94 | PTGER4 (0.65) | PTGER4PTGER2MRGPRX4PTGER1PTGDR | |
| SCHEMBL2492541 | 0.94 | PTGER4 (0.65) | PTGER4PTGER2MRGPRX4PTGER1PTGDR | |
| SCHEMBL692475 | 0.92 | PTGER4 (0.68) | PTGER4PTGER2MRGPRX4PTGER1PTGDR | |
| SCHEMBL692208 | 0.91 | PTGER4 (0.64) | PTGER4PTGER2MRGPRX4PTGER1PTGDR | |
| SCHEMBL4014045 | 0.91 | PTGER4 (0.61) | PTGER4PTGER2PTGER1 | |
| SCHEMBL692571 | 0.91 | PTGER4 (0.72) | PTGER4PTGER2PTGDR | |
| SCHEMBL690993 | 0.91 | PTGER4 (0.67) | PTGER4PTGER2MRGPRX4PTGER1PTGDR | |
| SCHEMBL26914664 | 0.91 | PTGER4 (0.67) | PTGER4PTGER2MRGPRX4PTGER1PTGDR | |
| SCHEMBL4014640 | 0.90 | PTGER4 (0.72) | PTGER4PTGER2MRGPRX4PTGER1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756043-B1 | ORTHO SUBSTITUTED ARYL OR HETEROARYL AMIDE COMPOUNDS | RAQUALIA PHARMA INC (JP) | 2009-07-01 | — | — | EP | disclosed |