SCHEMBL417414

SCHEMBL417414

NCCSCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10903154 1.00
SCHEMBL1691317 0.98
SCHEMBL7723019 0.89 LMNA (0.33)
Hydrochloric Acid SCHEMBL420266 0.81
SCHEMBL10959204 0.79 TDP1 (0.42)
SCHEMBL419239 0.77
SCHEMBL811215 0.77 LMNA (0.35)
SCHEMBL3770995 0.77 LMNA (0.35)
SCHEMBL3778734 0.77 LMNA (0.35)
SCHEMBL810661 0.77 LMNA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841484-B2 Partially fluorinated ureas and amides E I DU PONT DE NEMOURS AND COMPANY (US) 2014-09-23 US disclosed
EP-2215098-B1 FLUOROALKYL SILANES DU PONT (US) 2014-08-20 EP disclosed
EP-2215056-B1 SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES DU PONT (US) 2013-10-30 EP disclosed
US-8501952-B2 Fluoroalkyl silanes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-08-06 US disclosed
US-8420826-B2 Fluoroalkyl silanes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-04-16 US disclosed
US-20120309853-A1 ALDOHEXOSE-BASED FLUOROADDITIVES E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-06 US disclosed
US-20120309854-A1 ALDOHEXOSE-BASED FLUOROADDITIVES E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-06 US disclosed
EP-2346923-B1 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS DU PONT (US) 2012-11-21 EP disclosed
US-8153846-B2 Sulfur containing fluoroalkyl amines and isocyanates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-04-10 US disclosed
US-20120022266-A1 FLUOROALKYL SILANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-26 US disclosed
US-8044239-B2 Partially fluorinated ureas and amides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-10-25 US disclosed
US-8026289-B2 Fluorinated polyoxyalkylene glycol diamide surfactants E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-27 US disclosed
EP-2346923-A2 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E. I. du Pont de Nemours and Company (US) 2011-07-27 EP disclosed
EP-2215098-A1 FLUOROALKYL SILANES E. I. du Pont de Nemours and Company (US) 2010-08-11 EP disclosed
WO-2010048248-A2 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-29 WO disclosed
US-20100099839-A1 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-22 US disclosed
WO-2009073595-A1 FLUOROALKYL SILANES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 WO disclosed
US-20090143608-A1 SULFUR CONTAINING FLUOROALKYL AMINES AND ISOCYANATES E. I. DU PONT DE NEMOURS AND COMPNAY 2009-06-04 US disclosed
US-20090143598-A1 FLUOROSILANES E.I. DU PONT DE NEMOURS AND COMPANY 2009-06-04 US disclosed
US-20090047435-A1 PARTIALLY FLUORINATED UREAS AND AMIDES E. I. DU PONT DE NEMOURS AND COMPANY 2009-02-19 US disclosed