Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239232 | 0.92 | NPSR1 (0.42) | PPARGKMT2ANPSR1TDP1F2 | |
| Hydrochloric Acid SCHEMBL9598758 | 0.91 | NPSR1 (0.41) | PPARGKMT2ANPSR1TDP1F2 | |
| SCHEMBL4175369 | 0.91 | F2 (0.42) | PPARGKMT2ANPSR1F2TSHR | |
| SCHEMBL13940140 | 0.88 | KMT2A (0.39) | KMT2ANPSR1BRD4TDP1TSHR | |
| SCHEMBL9157509 | 0.82 | CYP3A4 (0.50) | KMT2ANPSR1TDP1TSHRLMNA | |
| SCHEMBL9603542 | 0.82 | HTR6 (0.47) | KMT2ANPSR1TDP1TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9655914 | 0.82 | CYP3A4 (0.49) | KMT2ANPSR1TDP1TSHRLMNA | |
| SCHEMBL4162892 | 0.81 | MAPT (0.44) | KMT2ANPSR1TDP1TSHRLMNA | |
| SCHEMBL6451740 | 0.81 | MAPT (0.44) | PPARGNPSR1TDP1TSHRLMNA | |
| SCHEMBL8236467 | 0.81 | POLB (0.39) | KMT2ATDP1TSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090017112-A1 | Compounds for Inhibiting Beta-Amyloid Production | ROSKAMP RESEARCH LLC (US) | 2009-01-15 | — | — | US | disclosed |
| EP-1993548-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION | Roskamp Research LLC (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007103683-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION | ROSKAMP RESEARCH LLC (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007103683-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION | ROSKAMP RESEARCH LLC (US) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017112-A1 | Compounds for Inhibiting Beta-Amyloid Production | PSEN1, PSEN2, APP | PPARG 1742/4885KMT2A 4404/4885NPSR1 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.