SCHEMBL417493

SCHEMBL417493

O=C(CCc1ccccc1)Oc1ccc(O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.69
TDP1 Q9NUW8 1/20 0.58
HPGD P15428 1/20 0.54
FFAR1 O14842 5/20 0.53
FFAR4 Q5NUL3 1/20 0.53
PDGFRB P09619 1/20 0.50
PDGFRA P16234 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
CYP2C19 P33261 1/20 0.50
PTGS2 P35354 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HIF1A Q16665 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
KEAP1 Q14145 1/20 0.50
DPP4 P27487 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17951284 0.93 KMT2A (0.78) KMT2ATDP1HPGDFFAR1FFAR4
SCHEMBL19757253 0.91 KMT2A (0.57) KMT2ATDP1HPGDFFAR1FFAR4
SCHEMBL28224031 0.91 KMT2A (0.57) KMT2ATDP1HPGDFFAR1FFAR4
SCHEMBL19497935 0.91 FFAR1 (0.68) KMT2AFFAR1FFAR4LMNACYP1A2
SCHEMBL419310 0.90 KMT2A (0.57) KMT2ATDP1HPGDFFAR1LMNA
SCHEMBL1050111 0.89 KMT2A (0.73) KMT2ATDP1HPGDFFAR1FFAR4
SCHEMBL10882168 0.87 KMT2A (0.71) KMT2ATDP1HPGDFFAR1FFAR4
SCHEMBL27537713 0.87 KMT2A (0.71) KMT2ATDP1HPGDFFAR1FFAR4
Hydrogen Sulfide SCHEMBL28066373 0.87 KMT2A (0.71) KMT2ATDP1HPGDFFAR1FFAR4
Hydrogen Sulfide SCHEMBL27894387 0.87 KMT2A (0.71) KMT2ATDP1HPGDFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4502066-A STABILIZERS OF P-ALKYL- OR O-BENZOYLBENZOIC ACID METAL SALTS; OIL REPELLANTS JUJO PAPER CO., LTD. (JP) 1985-02-26 US claimed
CN-114006126-B Lithium-sulfur battery diaphragm material and preparation method thereof 东北师范大学 2023-06-13 CN disclosed
CN-115974687-A Preparation method of hydroquinone ester derivative with tyrosinase inhibitory activity 西南林业大学 2023-04-18 CN disclosed
CN-114006126-A Lithium-sulfur battery diaphragm material and preparation method thereof 东北师范大学 2022-02-01 CN disclosed
CN-107636085-A Water-based jet ink 爱克发-格法特公司 2018-01-26 CN disclosed
US-9133104-B2 Enzyme inhibitors CHROMA THERAPEUTICS LTD. (GB) 2015-09-15 US disclosed
CN-101837337-B Method and apparatus for producing thermosensitive recording material RICOH CO LTD 2015-01-14 CN disclosed
CN-102205757-B Thermosensitive recording medium RICOH CO.,LTD. (JP) 2014-10-01 CN disclosed
US-8753721-B2 Method and apparatus for producing thermosensitive recording material RICOH COMPANY, LTD. (JP) 2014-06-17 US disclosed
US-20140163042-A1 ENZYME INHIBITORS CHROMA THERAPEUTICS LTD. (GB) 2014-06-12 US disclosed
US-5763463-A Pyridine compounds which are useful as pesticides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-06-09 US disclosed
EP-0764635-A1 DIPHENYL SULFONE DERIVATIVE AND RECORDING MATERIAL PREPARED THEREFROM NIPPON SODA CO., LTD. (JP) 1997-03-26 EP disclosed
EP-0623594-B1 PHENETHYL ALCOHOL DERIVATIVE AND RECORDING MATERIAL CONTAINING THE SAME NIPPON SODA CO (JP) 1996-12-27 EP disclosed
US-5463133-A Stabilizing agent for colored images, color developer NIPPON SODA CO., LTD. (JP) 1995-10-31 US disclosed
EP-0623594-A1 PHENETHYL ALCOHOL DERIVATIVE AND RECORDING MATERIAL CONTAINING THE SAME NIPPON SODA CO., LTD. (JP) 1994-11-09 EP disclosed
US-5229381-A Inhibitors of leukocyte enzyme elastase MERCK & CO., INC. (US) 1993-07-20 US disclosed
EP-0481671-A1 New substituted azetidinones as anti-inflammatory and antidegenerative agents MERCK & CO. INC. (US) 1992-04-22 EP disclosed
US-4591888-A IMPROVED STABILITY AGAINST CONTAMINATION WITH OILY SUBSTANCES JUJO PAPER CO., LTD. (JP) 1986-05-27 US disclosed
US-4590500-A POLYUALENT METAL SALTS OF A PHTHALIC ACID MONOESTER AS STABILIZER; OIL REPELLENTS; ANTISIOLANTS; BRIGHT BACKGROUND JUJO PAPER CO., LTD. (JP) 1986-05-20 US disclosed
US-4502066-A STABILIZERS OF P-ALKYL- OR O-BENZOYLBENZOIC ACID METAL SALTS; OIL REPELLANTS JUJO PAPER CO., LTD. (JP) 1985-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140163042-A1 ENZYME INHIBITORS HAT1, NR2E1, HDAC3 KMT2A 177/4885TDP1 1950/4885HPGD 2764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.