SCHEMBL419310

SCHEMBL419310

O=C(CCCc1ccccc1)Oc1ccc(O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.57
HPGD P15428 2/20 0.56
TRPV1 Q8NER1 2/20 0.55
DPP4 P27487 1/20 0.54
HDAC6 Q9UBN7 4/20 0.53
HDAC3 O15379 3/20 0.53
HDAC1 Q13547 3/20 0.53
HDAC2 Q92769 3/20 0.53
HDAC8 Q9BY41 3/20 0.53
HDAC5 Q9UQL6 3/20 0.53
HDAC4 P56524 2/20 0.53
HDAC7 Q8WUI4 2/20 0.53
HDAC10 Q969S8 2/20 0.53
HDAC11 Q96DB2 2/20 0.53
HDAC9 Q9UKV0 2/20 0.53
SLC6A3 Q01959 2/20 0.53
MAPK1 P28482 1/20 0.53
ADRA1A P35348 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PLAAT3 P53816 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27587646 0.94 TRPV1 (0.54) KMT2AHPGDTRPV1DPP4HDAC6
SCHEMBL9466128 0.92 CALM1 (0.53) KMT2AHPGDTRPV1PLAAT3PLAAT5
SCHEMBL417493 0.90 KMT2A (0.69) KMT2AHPGDTRPV1DPP4HDAC6
SCHEMBL112611 0.90 HDAC1 (0.60) KMT2AHPGDHDAC6HDAC3HDAC1
SCHEMBL28863969 0.89 DPP4 (0.56) KMT2AHPGDTRPV1DPP4PLAAT3
SCHEMBL29113880 0.88 HDAC1 (0.58) KMT2AHPGDHDAC6HDAC3HDAC1
SCHEMBL34470327 0.87 KMT2A (0.57) KMT2AHPGDHDAC6HDAC3HDAC1
SCHEMBL27975142 0.87 KMT2A (0.53) KMT2AHPGDDPP4SLC6A3LMNA
SCHEMBL27491472 0.86 KMT2A (0.56) KMT2AHPGDHDAC6HDAC3HDAC1
SCHEMBL9078593 0.85 PRSS1 (0.60) KMT2AHPGDDPP4HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107199794-A Thermal recording medium containing chelating agent 株式会社理光 2017-09-26 CN disclosed
CN-101837337-B Method and apparatus for producing thermosensitive recording material RICOH CO LTD 2015-01-14 CN disclosed
CN-102205757-B Thermosensitive recording medium RICOH CO.,LTD. (JP) 2014-10-01 CN disclosed
US-8753721-B2 Method and apparatus for producing thermosensitive recording material RICOH COMPANY, LTD. (JP) 2014-06-17 US disclosed
CN-102152681-B Thermosensitive recording material and image recording method RICOH CO LTD 2014-04-09 CN disclosed
CN-101670721-B Thermosensitive recording material RICOH CO LTD 2012-12-05 CN disclosed
US-8193116-B2 Heat-sensitive recording material RICOH COMPANY, LTD. (JP) 2012-06-05 US disclosed
US-20120021900-A1 HEAT-SENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2012-01-26 US disclosed
CN-102211483-A Thermosensitive recording medium RICOH CO LTD 2011-10-12 CN disclosed
CN-102205757-A Thermosensitive recording medium RICOH CO LTD 2011-10-05 CN disclosed
CN-102152681-A Thermosensitive recording material and image recording method RICOH CO LTD 2011-08-17 CN disclosed
CN-102066123-A Color-developing composition and recording material containing same NIPPON SODA CO 2011-05-18 CN disclosed
US-20100239766-A1 Method And Apparatus For Producing Thermosensitive Recording Material RICOH COMPANY, LTD. (JP) 2010-09-23 US disclosed
CN-101837337-A Method and apparatus for producing thermosensitive recording material RICOH KK 2010-09-22 CN disclosed
CN-101670721-A Thermosensitive recording material RICOH KK 2010-03-17 CN disclosed
US-5837452-A HEATING CELLS IN SOLUTION CONTAINING NONIONIC SURFACTANT DETERGENT AND CHELATE COMPOUND GEN-PROBE INCORPORATED (US) 1998-11-17 US disclosed
WO-1994028420-A1 METHOD OF DETECTION OF BACTERIA RHONE POULENC DIAGNOSTICS LTD (GB) 1994-12-08 WO disclosed